HSP70-Mediated NLRP3 Inflammasome Suppression Underlies Reversal of Acute Kidney Injury Following Extracellular Vesicle and Focused Ultrasound Combination Therapy

Acute kidney injury (AKI) is the abrupt loss of renal function, for which only supportive therapies exist. Mesenchymal stromal cell (MSC)-derived extracellular vesicles (EVs) have been shown to be therapeutically effective in treating AKI by spurring endogenous cell proliferation and survival while...

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Detalles Bibliográficos
Autores principales: Ullah, Mujib, Liu, Daniel D., Rai, Sravanthi, Concepcion, Waldo, Thakor, Avnesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312940/
https://www.ncbi.nlm.nih.gov/pubmed/32521623
http://dx.doi.org/10.3390/ijms21114085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312940/
https://www.ncbi.nlm.nih.gov/pubmed/32521623
http://dx.doi.org/10.3390/ijms21114085

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