Cargando…
HSP70-Mediated NLRP3 Inflammasome Suppression Underlies Reversal of Acute Kidney Injury Following Extracellular Vesicle and Focused Ultrasound Combination Therapy
Acute kidney injury (AKI) is the abrupt loss of renal function, for which only supportive therapies exist. Mesenchymal stromal cell (MSC)-derived extracellular vesicles (EVs) have been shown to be therapeutically effective in treating AKI by spurring endogenous cell proliferation and survival while...
Autores principales: | Ullah, Mujib, Liu, Daniel D., Rai, Sravanthi, Concepcion, Waldo, Thakor, Avnesh S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312940/ https://www.ncbi.nlm.nih.gov/pubmed/32521623 http://dx.doi.org/10.3390/ijms21114085 |
Ejemplares similares
-
Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury
por: Ullah, Mujib, et al.
Publicado: (2020) -
Reversing Acute Kidney Injury Using Pulsed Focused Ultrasound and MSC Therapy: A Role for HSP-Mediated PI3K/AKT Signaling
por: Ullah, Mujib, et al.
Publicado: (2020) -
Stem cell-derived extracellular vesicles: role in oncogenic processes, bioengineering potential, and technical challenges
por: Ullah, Mujib, et al.
Publicado: (2019) -
A Novel Approach to Deliver Therapeutic Extracellular Vesicles Directly into the Mouse Kidney via Its Arterial Blood Supply
por: Ullah, Mujib, et al.
Publicado: (2020) -
The role of ultrasound in enhancing mesenchymal stromal cell‐based therapies
por: Liu, Daniel D., et al.
Publicado: (2020)