The Impact of Single- and Double-Strand DNA Breaks in Human Spermatozoa on Assisted Reproduction

Several cellular insults can result in sperm DNA fragmentation either on one or both DNA strands. Oxidative damage, premature interruption of the apoptotic process and defects in DNA compaction during spermatogenesis are the main mechanisms that cause DNA breaks in sperm. The two-tailed Comet assay...

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Detalles Bibliográficos
Autores principales: Agarwal, Ashok, Barbăroșie, Cătălina, Ambar, Rafael, Finelli, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312948/
https://www.ncbi.nlm.nih.gov/pubmed/32485940
http://dx.doi.org/10.3390/ijms21113882

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