Cargando…

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion

Minor splicing plays an important role in vertebrate development. Zrsr1 and Zrsr2 paralog genes have essential roles in alternative splicing, mainly participating in the recognition of minor (U12) introns. To further explore their roles during early embryo development, we produced Zrsr1(mu) and Zrsr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gómez-Redondo, Isabel, Ramos-Ibeas, Priscila, Pericuesta, Eva, Fernández-González, Raúl, Laguna-Barraza, Ricardo, Gutiérrez-Adán, Alfonso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312986/ https://www.ncbi.nlm.nih.gov/pubmed/32527007 http://dx.doi.org/10.3390/ijms21114115

Ejemplares similares

Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development
por: Gómez-Redondo, Isabel, et al.
Publicado: (2022)

Sex-Dimorphic Behavioral Alterations and Altered Neurogenesis in U12 Intron Splicing-Defective Zrsr1 Mutant Mice
por: Alén, Francisco, et al.
Publicado: (2019)

Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice
por: Garcia-Ruiz, Cristian, et al.
Publicado: (2022)

ZRSR1 co-operates with ZRSR2 in regulating splicing of U12-type introns in murine hematopoietic cells
por: Madan, Vikas, et al.
Publicado: (2021)

Zrsr2 Is Essential for the Embryonic Development and Splicing of Minor Introns in RNA and Protein Processing Genes in Zebrafish
por: Weinstein, Rachel, et al.
Publicado: (2022)

Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome
por: Madan, Vikas, et al.
Publicado: (2015)

ZRSR2 overexpression is a frequent and early event in castration-resistant prostate cancer development
por: He, Haiqing, et al.
Publicado: (2021)

Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis
por: Togami, Katsuhiro, et al.
Publicado: (2022)

Intracytoplasmic Sperm Injection Using DNA-Fragmented Sperm in Mice Negatively Affects Embryo-Derived Embryonic Stem Cells, Reduces the Fertility of Male Offspring and Induces Heritable Changes in Epialleles
por: Ramos-Ibeas, Priscila, et al.
Publicado: (2014)

RF02 | PMON323 Pituitary stalk interruption syndrome, polydactyly, polymicrogyria and a ZRSR2 variant
por: Jacobs, An, et al.
Publicado: (2022)

Growing oocyte-specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR
por: Joh, Keiichiro, et al.
Publicado: (2018)

D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome
por: Pericuesta, Eva, et al.
Publicado: (2020)

Successful ICSI in Mice Using Caput Epididymal Spermatozoa
por: Fernández-González, Raúl, et al.
Publicado: (2019)

Identification of the new gene Zrsr1 to associate with the pluripotency state in induced pluripotent stem cells (iPSCs) using high throughput sequencing technology
por: Gao, Shuai, et al.
Publicado: (2014)

Loss of the importin Kpna2 causes infertility in male mice by disrupting the translocation of testis-specific transcription factors
por: Navarrete-López, Paula, et al.
Publicado: (2023)

Potential Health Risks Associated to ICSI: Insights from Animal Models and Strategies for a Safe Procedure
por: Sánchez-Calabuig, María Jesús, et al.
Publicado: (2014)

Differential isoform expression and alternative splicing in sex determination in mice
por: Planells, Benjamín, et al.
Publicado: (2019)

Senescence and Apoptosis During in vitro Embryo Development in a Bovine Model
por: Ramos-Ibeas, Priscila, et al.
Publicado: (2020)

An ancient testis-specific IQ motif-containing H gene regulates specific transcript isoform expression during spermatogenesis
por: Navarrete-López, Paula, et al.
Publicado: (2023)

Directions and applications of CRISPR technology in livestock research
por: Lamas-Toranzo, IsmaeI, et al.
Publicado: (2018)

Antioxidant Nobiletin Enhances Oocyte Maturation and Subsequent Embryo Development and Quality
por: Cajas, Yulia N., et al.
Publicado: (2020)

Sperm selection by thermotaxis improves ICSI outcome in mice
por: Pérez-Cerezales, Serafín, et al.
Publicado: (2018)

Prion Protein Expression Regulates Embryonic Stem Cell Pluripotency and Differentiation
por: Miranda, Alberto, et al.
Publicado: (2011)

Lineage Differentiation Markers as a Proxy for Embryo Viability in Farm Ungulates
por: Pérez-Gómez, Alba, et al.
Publicado: (2021)

Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells
por: Ramírez, Miguel A, et al.
Publicado: (2006)

Impact of Overuse and Sexually Transmitted Infections on Seminal Parameters of Extensively Managed Bulls
por: Montoya-Monsalve, Giovanni, et al.
Publicado: (2021)

TMEM95 is a sperm membrane protein essential for mammalian fertilization
por: Lamas-Toranzo, Ismael, et al.
Publicado: (2020)

Aberrant Alternative Splicing in U2af1/Tet2 Double Mutant Mice Contributes to Major Hematological Phenotypes
por: Martínez-Valiente, Cristina, et al.
Publicado: (2021)

Postnatal Catch-Up Growth Programs Telomere Dynamics and Glucose Intolerance in Low Birth Weight Mice
por: Pericuesta, Eva, et al.
Publicado: (2021)

In vitro culture of ovine embryos up to early gastrulating stages
por: Ramos-Ibeas, Priscila, et al.
Publicado: (2022)

Embryonic disc formation following post-hatching bovine embryo development in vitro
por: Ramos-Ibeas, Priscila, et al.
Publicado: (2020)

Transcriptome profiling of liver of non-genetic low birth weight and long term health consequences
por: Miranda, Alberto, et al.
Publicado: (2014)

The Role of Aquaporin 7 in the Movement of Water and Cryoprotectants in Bovine In Vitro Matured Oocytes
por: García-Martínez, Tania, et al.
Publicado: (2022)

MISF2 Encodes an Essential Mitochondrial Splicing Cofactor Required for nad2 mRNA Processing and Embryo Development in Arabidopsis thaliana
por: Nguyen, Tan-Trung, et al.
Publicado: (2022)

Minor intron splicing revisited: identification of new minor intron-containing genes and tissue-dependent retention and alternative splicing of minor introns
por: Olthof, Anouk M., et al.
Publicado: (2019)

The significant other: splicing by the minor spliceosome
por: Turunen, Janne J, et al.
Publicado: (2013)

Dysregulated minor intron splicing in cancer
por: Nishimura, Koutarou, et al.
Publicado: (2022)

Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis
por: Ramos-Ibeas, Priscila, et al.
Publicado: (2019)

Sox2 Is Essential for Formation of Trophectoderm in the Preimplantation Embryo
por: Keramari, Maria, et al.
Publicado: (2010)

Non-coding RNAs derived from the foot-and-mouth disease virus genome trigger broad antiviral activity against coronaviruses
por: Rodríguez-Pulido, Miguel, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_594oljpaqa1hmkgim39b3js8ia