Two cases of septic shock with different outcomes caused by non-O1/non-O139 Vibrio cholerae isolates

In recent decades, increasing numbers of human infections have been linked to non-O1/non-O139 Vibrio cholerae. Septicemia resulting from non-O1/non-O139 V. cholerae infection is rare but has high mortality. The pathogenesis of non-O1/non-O139 V. cholerae septicemia is poorly understood. Here, we rep...

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Autores principales: Chen, Jie, Huang, Jian, Huang, Meirong, Chen, Zehui, Chen, Anlin, Yang, Jianru, Zhang, Tao, Min, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313337/
https://www.ncbi.nlm.nih.gov/pubmed/32571124
http://dx.doi.org/10.1177/0300060520933459
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author Chen, Jie
Huang, Jian
Huang, Meirong
Chen, Zehui
Chen, Anlin
Yang, Jianru
Zhang, Tao
Min, Xun
author_facet Chen, Jie
Huang, Jian
Huang, Meirong
Chen, Zehui
Chen, Anlin
Yang, Jianru
Zhang, Tao
Min, Xun
author_sort Chen, Jie
collection PubMed
description In recent decades, increasing numbers of human infections have been linked to non-O1/non-O139 Vibrio cholerae. Septicemia resulting from non-O1/non-O139 V. cholerae infection is rare but has high mortality. The pathogenesis of non-O1/non-O139 V. cholerae septicemia is poorly understood. Here, we report two sporadic cases of septicemia following non-O1/non-O139 V. cholerae infection from an inland area of China. Patient 1 died rapidly within 24 hours, while patient 2 gradually recovered from septic shock. To explore the reasons for these divergent outcomes, we compared the two cases, tested the antibiotic sensitivity of the two isolates, and investigated their virulence genes and sequence types.
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spelling pubmed-73133372020-07-06 Two cases of septic shock with different outcomes caused by non-O1/non-O139 Vibrio cholerae isolates Chen, Jie Huang, Jian Huang, Meirong Chen, Zehui Chen, Anlin Yang, Jianru Zhang, Tao Min, Xun J Int Med Res Case Report In recent decades, increasing numbers of human infections have been linked to non-O1/non-O139 Vibrio cholerae. Septicemia resulting from non-O1/non-O139 V. cholerae infection is rare but has high mortality. The pathogenesis of non-O1/non-O139 V. cholerae septicemia is poorly understood. Here, we report two sporadic cases of septicemia following non-O1/non-O139 V. cholerae infection from an inland area of China. Patient 1 died rapidly within 24 hours, while patient 2 gradually recovered from septic shock. To explore the reasons for these divergent outcomes, we compared the two cases, tested the antibiotic sensitivity of the two isolates, and investigated their virulence genes and sequence types. SAGE Publications 2020-06-22 /pmc/articles/PMC7313337/ /pubmed/32571124 http://dx.doi.org/10.1177/0300060520933459 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Chen, Jie
Huang, Jian
Huang, Meirong
Chen, Zehui
Chen, Anlin
Yang, Jianru
Zhang, Tao
Min, Xun
Two cases of septic shock with different outcomes caused by non-O1/non-O139 Vibrio cholerae isolates
title Two cases of septic shock with different outcomes caused by non-O1/non-O139 Vibrio cholerae isolates
title_full Two cases of septic shock with different outcomes caused by non-O1/non-O139 Vibrio cholerae isolates
title_fullStr Two cases of septic shock with different outcomes caused by non-O1/non-O139 Vibrio cholerae isolates
title_full_unstemmed Two cases of septic shock with different outcomes caused by non-O1/non-O139 Vibrio cholerae isolates
title_short Two cases of septic shock with different outcomes caused by non-O1/non-O139 Vibrio cholerae isolates
title_sort two cases of septic shock with different outcomes caused by non-o1/non-o139 vibrio cholerae isolates
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313337/
https://www.ncbi.nlm.nih.gov/pubmed/32571124
http://dx.doi.org/10.1177/0300060520933459
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