Identification of Target Genes and Transcription Factors in Mice with LMNA-Related Dilated Cardiomyopathy by Integrated Bioinformatic Analyses

BACKGROUND: Dilated cardiomyopathy (DCM), which is characterized by enlarged ventricular dimensions and systolic dysfunction, is the most common type of cardiomyopathy. Mutations in the LMNA gene are reported in approximately 10% of familial DCM cases. However, the mechanism of LMNA mutations in hum...

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Detalles Bibliográficos
Autores principales: Zhou, Honghua, Tan, Liao, Lu, Ting, Xu, Kai, Li, Chan, Liu, Zhaoya, Peng, Huihui, Shi, RuiZheng, Zhang, Guogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Database Analysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313426/
https://www.ncbi.nlm.nih.gov/pubmed/32581210
http://dx.doi.org/10.12659/MSM.924576

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