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Emerging Pharmaceutical Treatments of Novel COVID-19: A Review

As a new decade began, COVID-19 quickly gained importance as it became the cause of the current global pandemic. Research has been focusing on studying the structure of SARS-CoV-2 and investigates possible pharmaceutical approaches. With the number of cases increasing every day, globally, multiple d...

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Detalles Bibliográficos
Autores principales: Hussain, Azhar, Kaler, Jasndeep, Dubey, Arun Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313429/
https://www.ncbi.nlm.nih.gov/pubmed/32596078
http://dx.doi.org/10.7759/cureus.8260
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author Hussain, Azhar
Kaler, Jasndeep
Dubey, Arun Kumar
author_facet Hussain, Azhar
Kaler, Jasndeep
Dubey, Arun Kumar
author_sort Hussain, Azhar
collection PubMed
description As a new decade began, COVID-19 quickly gained importance as it became the cause of the current global pandemic. Research has been focusing on studying the structure of SARS-CoV-2 and investigates possible pharmaceutical approaches. With the number of cases increasing every day, globally, multiple drugs are being researched as possible candidates. Although multiple drugs show promise in the treatment of COVID-19 via either inhibiting viral replication or preventing fusion of the virus to the ACE2 receptors, further investigation is still warranted and necessary before the admission of any type of pharmaceutical agent. Furthermore, several supplements have also been documented in being utilized as treatment of COVID-19. The exact mechanism and efficacy of current candidate drugs are still being explored through clinical trials. Despite the advancements in current research with emerging treatments, social distancing and engaging in preventative measures remains crucial to attempt to prevent the occurrence of more cases and deaths, worldwide. This review explores various drugs and their mechanism of action which are either currently being used in clinical trials or may be used in the future for the treatment of COVID-19.
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spelling pubmed-73134292020-06-26 Emerging Pharmaceutical Treatments of Novel COVID-19: A Review Hussain, Azhar Kaler, Jasndeep Dubey, Arun Kumar Cureus Emergency Medicine As a new decade began, COVID-19 quickly gained importance as it became the cause of the current global pandemic. Research has been focusing on studying the structure of SARS-CoV-2 and investigates possible pharmaceutical approaches. With the number of cases increasing every day, globally, multiple drugs are being researched as possible candidates. Although multiple drugs show promise in the treatment of COVID-19 via either inhibiting viral replication or preventing fusion of the virus to the ACE2 receptors, further investigation is still warranted and necessary before the admission of any type of pharmaceutical agent. Furthermore, several supplements have also been documented in being utilized as treatment of COVID-19. The exact mechanism and efficacy of current candidate drugs are still being explored through clinical trials. Despite the advancements in current research with emerging treatments, social distancing and engaging in preventative measures remains crucial to attempt to prevent the occurrence of more cases and deaths, worldwide. This review explores various drugs and their mechanism of action which are either currently being used in clinical trials or may be used in the future for the treatment of COVID-19. Cureus 2020-05-24 /pmc/articles/PMC7313429/ /pubmed/32596078 http://dx.doi.org/10.7759/cureus.8260 Text en Copyright © 2020, Hussain et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Hussain, Azhar
Kaler, Jasndeep
Dubey, Arun Kumar
Emerging Pharmaceutical Treatments of Novel COVID-19: A Review
title Emerging Pharmaceutical Treatments of Novel COVID-19: A Review
title_full Emerging Pharmaceutical Treatments of Novel COVID-19: A Review
title_fullStr Emerging Pharmaceutical Treatments of Novel COVID-19: A Review
title_full_unstemmed Emerging Pharmaceutical Treatments of Novel COVID-19: A Review
title_short Emerging Pharmaceutical Treatments of Novel COVID-19: A Review
title_sort emerging pharmaceutical treatments of novel covid-19: a review
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313429/
https://www.ncbi.nlm.nih.gov/pubmed/32596078
http://dx.doi.org/10.7759/cureus.8260
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