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Occupation of a thermoresistant-scaffold (αRep) at SP1-NC cleavage site disturbs the function of HIV-1 protease

HIV-1 nucleocapsid (NC) becomes an attractive target for the development of novel anti-HIV-1 agents. Discovering of non-antibody scaffolds that disrupt the function of NC will be a potential aspect for disturbing viral maturation process. Correspondingly, we explored the specific binding site of the...

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Detalles Bibliográficos
Autores principales:	Hadpech, Sudarat, Peerakam, Nichakan, Chupradit, Koollawat, Tayapiwatana, Chatchai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Molecular Scaffolds & Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313444/ https://www.ncbi.nlm.nih.gov/pubmed/32519747 http://dx.doi.org/10.1042/BSR20201131

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