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A Neuroprotective Dose of Isatin Causes Multilevel Changes Involving the Brain Proteome: Prospects for Further Research

Isatin (indole-2,3-dione) is an endogenous regulator, exhibiting a wide range of biological and pharmacological activities. At doses of 100 mg/kg and above, isatin is neuroprotective in different experimental models of neurodegeneration. Good evidence exists that its effects are realized via interac...

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Detalles Bibliográficos
Autores principales: Medvedev, Alexei, Kopylov, Arthur, Buneeva, Olga, Kurbatov, Leonid, Tikhonova, Olga, Ivanov, Alexis, Zgoda, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313464/
https://www.ncbi.nlm.nih.gov/pubmed/32545384
http://dx.doi.org/10.3390/ijms21114187

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