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A Neuroprotective Dose of Isatin Causes Multilevel Changes Involving the Brain Proteome: Prospects for Further Research
Isatin (indole-2,3-dione) is an endogenous regulator, exhibiting a wide range of biological and pharmacological activities. At doses of 100 mg/kg and above, isatin is neuroprotective in different experimental models of neurodegeneration. Good evidence exists that its effects are realized via interac...
Autores principales: | Medvedev, Alexei, Kopylov, Arthur, Buneeva, Olga, Kurbatov, Leonid, Tikhonova, Olga, Ivanov, Alexis, Zgoda, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313464/ https://www.ncbi.nlm.nih.gov/pubmed/32545384 http://dx.doi.org/10.3390/ijms21114187 |
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