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Repeat induces not only gene silencing, but also gene activation in mammalian cells

Repeat-induced gene silencing (RIGS) establishes the centromere structure, prevents the spread of transposons and silences transgenes, thereby limiting recombinant protein production. We previously isolated a sequence (B-3-31) that alleviates RIGS from the human genome. Here, we developed an assay s...

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Detalles Bibliográficos
Autores principales:	Ogaki, Yusuke, Fukuma, Miki, Shimizu, Noriaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313748/ https://www.ncbi.nlm.nih.gov/pubmed/32579599 http://dx.doi.org/10.1371/journal.pone.0235127

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