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Are in vitro and in silico approaches used appropriately for animal-based major depressive disorder research?
The current paradigm for biomedical research and drug testing postulates that in vitro and in silico data inform animal studies that will subsequently inform human studies. Recent evidence points out that animal studies have made a poor contribution to current knowledge of Major Depressive Disorder,...
Autores principales: | Carvalho, Constança, Varela, Susana A. M., Marques, Tiago A., Knight, Andrew, Vicente, Luís |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313753/ https://www.ncbi.nlm.nih.gov/pubmed/32579547 http://dx.doi.org/10.1371/journal.pone.0233954 |
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