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Are in vitro and in silico approaches used appropriately for animal-based major depressive disorder research?

The current paradigm for biomedical research and drug testing postulates that in vitro and in silico data inform animal studies that will subsequently inform human studies. Recent evidence points out that animal studies have made a poor contribution to current knowledge of Major Depressive Disorder,...

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Detalles Bibliográficos
Autores principales: Carvalho, Constança, Varela, Susana A. M., Marques, Tiago A., Knight, Andrew, Vicente, Luís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313753/
https://www.ncbi.nlm.nih.gov/pubmed/32579547
http://dx.doi.org/10.1371/journal.pone.0233954

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