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A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation
BACKGROUND: Severe acute respiratory syndrome coronavirus 2, the pathogen causing novel coronavirus disease of 2019 (COVID-19), efficiently spreads from person to person in close contact settings. Transmission among casual contacts in settings such as during social gatherings is not well understood....
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313868/ https://www.ncbi.nlm.nih.gov/pubmed/32613025 http://dx.doi.org/10.1093/ofid/ofaa231 |
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author | Shen, Ye Xu, Wenjie Li, Changwei Handel, Andreas Martinez, Leonardo Ling, Feng Ebell, Mark Fu, Xiaofei Pan, Jinren Ren, Jiangping Gu, Weiling Chen, Enfu |
author_facet | Shen, Ye Xu, Wenjie Li, Changwei Handel, Andreas Martinez, Leonardo Ling, Feng Ebell, Mark Fu, Xiaofei Pan, Jinren Ren, Jiangping Gu, Weiling Chen, Enfu |
author_sort | Shen, Ye |
collection | PubMed |
description | BACKGROUND: Severe acute respiratory syndrome coronavirus 2, the pathogen causing novel coronavirus disease of 2019 (COVID-19), efficiently spreads from person to person in close contact settings. Transmission among casual contacts in settings such as during social gatherings is not well understood. METHODS: We report several transmission events to both close and casual contacts from a cluster of 7 COVID-19 cases occurring from mid-January to early February 2020. A total of 539 social and family contacts of the index patient’s, including members of a 2-day wedding and a family party, were contacted and screened through epidemiologic surveys. The clinical progression of all cases is described. RESULTS: We estimate the secondary attack rate among close contacts to be 29% (2 of 7) and for the casual contacts to be 0.6% (3 of 473). The incubation period of our case cluster was 4–12 days (median, 7 days). CONCLUSIONS: Transmission efficiency among close contacts was higher than among casual contacts; however, transmission from second-generation cases may help spread the virus during the incubation period. |
format | Online Article Text |
id | pubmed-7313868 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-73138682020-06-25 A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation Shen, Ye Xu, Wenjie Li, Changwei Handel, Andreas Martinez, Leonardo Ling, Feng Ebell, Mark Fu, Xiaofei Pan, Jinren Ren, Jiangping Gu, Weiling Chen, Enfu Open Forum Infect Dis Major Article BACKGROUND: Severe acute respiratory syndrome coronavirus 2, the pathogen causing novel coronavirus disease of 2019 (COVID-19), efficiently spreads from person to person in close contact settings. Transmission among casual contacts in settings such as during social gatherings is not well understood. METHODS: We report several transmission events to both close and casual contacts from a cluster of 7 COVID-19 cases occurring from mid-January to early February 2020. A total of 539 social and family contacts of the index patient’s, including members of a 2-day wedding and a family party, were contacted and screened through epidemiologic surveys. The clinical progression of all cases is described. RESULTS: We estimate the secondary attack rate among close contacts to be 29% (2 of 7) and for the casual contacts to be 0.6% (3 of 473). The incubation period of our case cluster was 4–12 days (median, 7 days). CONCLUSIONS: Transmission efficiency among close contacts was higher than among casual contacts; however, transmission from second-generation cases may help spread the virus during the incubation period. Oxford University Press 2020-06-12 /pmc/articles/PMC7313868/ /pubmed/32613025 http://dx.doi.org/10.1093/ofid/ofaa231 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Major Article Shen, Ye Xu, Wenjie Li, Changwei Handel, Andreas Martinez, Leonardo Ling, Feng Ebell, Mark Fu, Xiaofei Pan, Jinren Ren, Jiangping Gu, Weiling Chen, Enfu A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation |
title | A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation |
title_full | A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation |
title_fullStr | A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation |
title_full_unstemmed | A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation |
title_short | A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation |
title_sort | cluster of novel coronavirus disease 2019 infections indicating person-to-person transmission among casual contacts from social gatherings: an outbreak case-contact investigation |
topic | Major Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313868/ https://www.ncbi.nlm.nih.gov/pubmed/32613025 http://dx.doi.org/10.1093/ofid/ofaa231 |
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