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A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation

BACKGROUND: Severe acute respiratory syndrome coronavirus 2, the pathogen causing novel coronavirus disease of 2019 (COVID-19), efficiently spreads from person to person in close contact settings. Transmission among casual contacts in settings such as during social gatherings is not well understood....

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Autores principales: Shen, Ye, Xu, Wenjie, Li, Changwei, Handel, Andreas, Martinez, Leonardo, Ling, Feng, Ebell, Mark, Fu, Xiaofei, Pan, Jinren, Ren, Jiangping, Gu, Weiling, Chen, Enfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313868/
https://www.ncbi.nlm.nih.gov/pubmed/32613025
http://dx.doi.org/10.1093/ofid/ofaa231
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author Shen, Ye
Xu, Wenjie
Li, Changwei
Handel, Andreas
Martinez, Leonardo
Ling, Feng
Ebell, Mark
Fu, Xiaofei
Pan, Jinren
Ren, Jiangping
Gu, Weiling
Chen, Enfu
author_facet Shen, Ye
Xu, Wenjie
Li, Changwei
Handel, Andreas
Martinez, Leonardo
Ling, Feng
Ebell, Mark
Fu, Xiaofei
Pan, Jinren
Ren, Jiangping
Gu, Weiling
Chen, Enfu
author_sort Shen, Ye
collection PubMed
description BACKGROUND: Severe acute respiratory syndrome coronavirus 2, the pathogen causing novel coronavirus disease of 2019 (COVID-19), efficiently spreads from person to person in close contact settings. Transmission among casual contacts in settings such as during social gatherings is not well understood. METHODS: We report several transmission events to both close and casual contacts from a cluster of 7 COVID-19 cases occurring from mid-January to early February 2020. A total of 539 social and family contacts of the index patient’s, including members of a 2-day wedding and a family party, were contacted and screened through epidemiologic surveys. The clinical progression of all cases is described. RESULTS: We estimate the secondary attack rate among close contacts to be 29% (2 of 7) and for the casual contacts to be 0.6% (3 of 473). The incubation period of our case cluster was 4–12 days (median, 7 days). CONCLUSIONS: Transmission efficiency among close contacts was higher than among casual contacts; however, transmission from second-generation cases may help spread the virus during the incubation period.
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spelling pubmed-73138682020-06-25 A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation Shen, Ye Xu, Wenjie Li, Changwei Handel, Andreas Martinez, Leonardo Ling, Feng Ebell, Mark Fu, Xiaofei Pan, Jinren Ren, Jiangping Gu, Weiling Chen, Enfu Open Forum Infect Dis Major Article BACKGROUND: Severe acute respiratory syndrome coronavirus 2, the pathogen causing novel coronavirus disease of 2019 (COVID-19), efficiently spreads from person to person in close contact settings. Transmission among casual contacts in settings such as during social gatherings is not well understood. METHODS: We report several transmission events to both close and casual contacts from a cluster of 7 COVID-19 cases occurring from mid-January to early February 2020. A total of 539 social and family contacts of the index patient’s, including members of a 2-day wedding and a family party, were contacted and screened through epidemiologic surveys. The clinical progression of all cases is described. RESULTS: We estimate the secondary attack rate among close contacts to be 29% (2 of 7) and for the casual contacts to be 0.6% (3 of 473). The incubation period of our case cluster was 4–12 days (median, 7 days). CONCLUSIONS: Transmission efficiency among close contacts was higher than among casual contacts; however, transmission from second-generation cases may help spread the virus during the incubation period. Oxford University Press 2020-06-12 /pmc/articles/PMC7313868/ /pubmed/32613025 http://dx.doi.org/10.1093/ofid/ofaa231 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Major Article
Shen, Ye
Xu, Wenjie
Li, Changwei
Handel, Andreas
Martinez, Leonardo
Ling, Feng
Ebell, Mark
Fu, Xiaofei
Pan, Jinren
Ren, Jiangping
Gu, Weiling
Chen, Enfu
A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation
title A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation
title_full A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation
title_fullStr A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation
title_full_unstemmed A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation
title_short A Cluster of Novel Coronavirus Disease 2019 Infections Indicating Person-to-Person Transmission Among Casual Contacts From Social Gatherings: An Outbreak Case-Contact Investigation
title_sort cluster of novel coronavirus disease 2019 infections indicating person-to-person transmission among casual contacts from social gatherings: an outbreak case-contact investigation
topic Major Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313868/
https://www.ncbi.nlm.nih.gov/pubmed/32613025
http://dx.doi.org/10.1093/ofid/ofaa231
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