A dopamine-induced gene expression signature regulates neuronal function and cocaine response

Drugs of abuse elevate dopamine levels in the nucleus accumbens (NAc) and alter transcriptional programs believed to promote long-lasting synaptic and behavioral adaptations. Here, we leveraged single-nucleus RNA-sequencing to generate a comprehensive molecular atlas of cell subtypes in the NAc, def...

Descripción completa

Detalles Bibliográficos
Autores principales: Savell, Katherine E., Tuscher, Jennifer J., Zipperly, Morgan E., Duke, Corey G., Phillips, Robert A., Bauman, Allison J., Thukral, Saakshi, Sultan, Faraz A., Goska, Nicholas A., Ianov, Lara, Day, Jeremy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314536/
https://www.ncbi.nlm.nih.gov/pubmed/32637607
http://dx.doi.org/10.1126/sciadv.aba4221

Ejemplares similares

Ejemplares similares