A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding

Microbial communities are self-controlled by repertoires of lethal agents, the antibiotics. In their turn, these antibiotics are regulated by bioscavengers that are selected in the course of evolution. Kinase-mediated phosphorylation represents one of the general strategies for the emergence of anti...

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Detalles Bibliográficos
Autores principales: Terekhov, Stanislav S., Mokrushina, Yuliana A., Nazarov, Anton S., Zlobin, Alexander, Zalevsky, Arthur, Bourenkov, Gleb, Golovin, Andrey, Belogurov, Alexey, Osterman, Ilya A., Kulikova, Alexandra A., Mitkevich, Vladimir A., Lou, Hua Jane, Turk, Benjamin E., Wilmanns, Matthias, Smirnov, Ivan V., Altman, Sidney, Gabibov, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314540/
https://www.ncbi.nlm.nih.gov/pubmed/32637600
http://dx.doi.org/10.1126/sciadv.aaz9861

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