A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation

Many annotated long noncoding RNAs (lncRNAs) harbor predicted short open reading frames (sORFs), but the coding capacities of these sORFs and the functions of the resulting micropeptides remain elusive. Here, we report that human lncRNA MIR155HG encodes a 17–amino acid micropeptide, which we termed...

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Detalles Bibliográficos
Autores principales: Niu, Liman, Lou, Fangzhou, Sun, Yang, Sun, Libo, Cai, Xiaojie, Liu, Zhaoyuan, Zhou, Hong, Wang, Hong, Wang, Zhikai, Bai, Jing, Yin, Qianqian, Zhang, Junxun, Chen, Linjiao, Peng, Danhong, Xu, Zhenyao, Gao, Yuanyuan, Tang, Sibei, Fan, Li, Wang, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314557/
https://www.ncbi.nlm.nih.gov/pubmed/32671205
http://dx.doi.org/10.1126/sciadv.aaz2059

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