Chimeric antigen receptor signaling: Functional consequences and design implications

Chimeric antigen receptor (CAR) T cell therapy has transformed the care of refractory B cell malignancies and holds tremendous promise for many aggressive tumors. Despite overwhelming scientific, clinical, and public interest in this rapidly expanding field, fundamental inquiries into CAR T cell mec...

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Detalles Bibliográficos
Autores principales: Lindner, S. E., Johnson, S. M., Brown, C. E., Wang, L. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314561/
https://www.ncbi.nlm.nih.gov/pubmed/32637585
http://dx.doi.org/10.1126/sciadv.aaz3223

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