Cargando…

Variation in mobility and exercise adaptations between Drosophila species

Locomotion and mobility have been studied extensively in Drosophila melanogaster but less is known about the locomotor capacity of other Drosophila species, while the response to chronic exercise in other species has yet to be examined. We have shown that adult male D. melanogaster adapt to exercise...

Descripción completa

Detalles Bibliográficos
Autores principales: Cobb, Tyler, Sujkowski, Alyson, Morton, Courtney, Ramesh, Divya, Wessells, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314734/
https://www.ncbi.nlm.nih.gov/pubmed/32335730
http://dx.doi.org/10.1007/s00359-020-01421-x
_version_ 1783550120196833280
author Cobb, Tyler
Sujkowski, Alyson
Morton, Courtney
Ramesh, Divya
Wessells, Robert
author_facet Cobb, Tyler
Sujkowski, Alyson
Morton, Courtney
Ramesh, Divya
Wessells, Robert
author_sort Cobb, Tyler
collection PubMed
description Locomotion and mobility have been studied extensively in Drosophila melanogaster but less is known about the locomotor capacity of other Drosophila species, while the response to chronic exercise in other species has yet to be examined. We have shown that adult male D. melanogaster adapt to exercise training with improved running endurance, climbing speed, and flight ability compared to unexercised flies. Here, we examine baseline mobility of D. sechellia, D. simulans, and D. virilis, and their response to chronic exercise training. We found significant interspecific differences in mobility and in the response to exercise. Although there is a significant sex difference in exercise adaptations in D. melanogaster, intraspecific analysis reveals few sex differences in other Drosophila species. As octopamine has been shown to be important for exercise adaptations in D. melanogaster, we also asked if any observed differences could be attributed to baseline octopamine levels. We find that octopamine and tyramine levels have the same rank order as baseline climbing speed and endurance in males, but do not predict the response to chronic exercise in males or females. Future research should focus on determining the mechanisms responsible for the inter- and intraspecific differences in mobility and the response to exercise. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00359-020-01421-x) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-7314734
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-73147342020-06-26 Variation in mobility and exercise adaptations between Drosophila species Cobb, Tyler Sujkowski, Alyson Morton, Courtney Ramesh, Divya Wessells, Robert J Comp Physiol A Neuroethol Sens Neural Behav Physiol Original Paper Locomotion and mobility have been studied extensively in Drosophila melanogaster but less is known about the locomotor capacity of other Drosophila species, while the response to chronic exercise in other species has yet to be examined. We have shown that adult male D. melanogaster adapt to exercise training with improved running endurance, climbing speed, and flight ability compared to unexercised flies. Here, we examine baseline mobility of D. sechellia, D. simulans, and D. virilis, and their response to chronic exercise training. We found significant interspecific differences in mobility and in the response to exercise. Although there is a significant sex difference in exercise adaptations in D. melanogaster, intraspecific analysis reveals few sex differences in other Drosophila species. As octopamine has been shown to be important for exercise adaptations in D. melanogaster, we also asked if any observed differences could be attributed to baseline octopamine levels. We find that octopamine and tyramine levels have the same rank order as baseline climbing speed and endurance in males, but do not predict the response to chronic exercise in males or females. Future research should focus on determining the mechanisms responsible for the inter- and intraspecific differences in mobility and the response to exercise. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00359-020-01421-x) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2020-04-25 2020 /pmc/articles/PMC7314734/ /pubmed/32335730 http://dx.doi.org/10.1007/s00359-020-01421-x Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Paper
Cobb, Tyler
Sujkowski, Alyson
Morton, Courtney
Ramesh, Divya
Wessells, Robert
Variation in mobility and exercise adaptations between Drosophila species
title Variation in mobility and exercise adaptations between Drosophila species
title_full Variation in mobility and exercise adaptations between Drosophila species
title_fullStr Variation in mobility and exercise adaptations between Drosophila species
title_full_unstemmed Variation in mobility and exercise adaptations between Drosophila species
title_short Variation in mobility and exercise adaptations between Drosophila species
title_sort variation in mobility and exercise adaptations between drosophila species
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314734/
https://www.ncbi.nlm.nih.gov/pubmed/32335730
http://dx.doi.org/10.1007/s00359-020-01421-x
work_keys_str_mv AT cobbtyler variationinmobilityandexerciseadaptationsbetweendrosophilaspecies
AT sujkowskialyson variationinmobilityandexerciseadaptationsbetweendrosophilaspecies
AT mortoncourtney variationinmobilityandexerciseadaptationsbetweendrosophilaspecies
AT rameshdivya variationinmobilityandexerciseadaptationsbetweendrosophilaspecies
AT wessellsrobert variationinmobilityandexerciseadaptationsbetweendrosophilaspecies