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ssGSEA score-based Ras dependency indexes derived from gene expression data reveal potential Ras addiction mechanisms with possible clinical implications
For nearly a decade, the difficulties associated with both the determination and reproducibility of Ras-dependency indexes (RDIs) have limited their application and further delineation of the biology underlying Ras dependency. In this report, we describe the application of a computational single sam...
Autores principales: | Yi, Ming, Nissley, Dwight V., McCormick, Frank, Stephens, Robert M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314760/ https://www.ncbi.nlm.nih.gov/pubmed/32581224 http://dx.doi.org/10.1038/s41598-020-66986-8 |
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