Metabolomic and Lipidomic Profiling of Bone Marrow Plasma Differentiates Patients with Monoclonal Gammopathy of Undetermined Significance from Multiple Myeloma

Oncogenic drivers of progression of monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) such as c-MYC have downstream effects on intracellular metabolic pathways of clonal plasma cells (PCs). Thus, extracellular environments such as the bone marrow (BM) plasma likely h...

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Detalles Bibliográficos
Autores principales: Gonsalves, Wilson I., Broniowska, Katarzyna, Jessen, Erik, Petterson, Xuan-Mai, Bush, Alexander Graham, Gransee, Jaimee, Lacy, Martha Q., Hitosugi, Taro, Kumar, Shaji K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314797/
https://www.ncbi.nlm.nih.gov/pubmed/32581232
http://dx.doi.org/10.1038/s41598-020-67105-3

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