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Evaluation of leakage resistance improvement in transconjunctival sutureless vitrectomy sclerotomies closed with adhesives. an experimental study

BACKGROUND: The purpose of this paper is to study the utility of adhesives (artificial-cyanoacrylate and biological-fibrin glue) for improving transconjunctival sutureless vitrectomy (TSV) sclerotomy closure competency. METHODS: Experimental and observer-masked study in which after performing TSV in...

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Autores principales: López-Guajardo, Lorenzo, Benítez-Herreros, Javier, Donate-López, Juan, Opazo-Toro, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314807/
https://www.ncbi.nlm.nih.gov/pubmed/31685969
http://dx.doi.org/10.1038/s41433-019-0651-4
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author López-Guajardo, Lorenzo
Benítez-Herreros, Javier
Donate-López, Juan
Opazo-Toro, Valeria
author_facet López-Guajardo, Lorenzo
Benítez-Herreros, Javier
Donate-López, Juan
Opazo-Toro, Valeria
author_sort López-Guajardo, Lorenzo
collection PubMed
description BACKGROUND: The purpose of this paper is to study the utility of adhesives (artificial-cyanoacrylate and biological-fibrin glue) for improving transconjunctival sutureless vitrectomy (TSV) sclerotomy closure competency. METHODS: Experimental and observer-masked study in which after performing TSV in cadaveric pig eyes, different adhesives were tested on sclerotomy entrances in order to determine if they improved closure competency in face of progressive intraocular pressure increase. In 76 eyes cyanoacrylate-treated sclerotomies were compared with sclerotomies in which no additional manoeuvre to aid closing was performed; in 76 eyes fibrin glue with no manoeuvre; and in the last 76 eyes, cyanoacrylate-treated sclerotomies were compared with fibrin glue-treated sclerotomies. RESULTS: A total of 228 eyes had a 23-gauge TSV performed. Both cyanoacrylate and fibrin glue treated sclerotomies achieved higher mean opening pressures when compared with nontreated sclerotomies in the same eye (p < 0.002). When cyanoacrylate was compared with biological adhesive in the same eye, no statistically significant differences were obtained (p = 0.216). DISCUSSIONS: This experimental study provides support for the possible role of adhesives in improving TSV sclerotomy closure competency in clinical practice.
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spelling pubmed-73148072020-06-26 Evaluation of leakage resistance improvement in transconjunctival sutureless vitrectomy sclerotomies closed with adhesives. an experimental study López-Guajardo, Lorenzo Benítez-Herreros, Javier Donate-López, Juan Opazo-Toro, Valeria Eye (Lond) Article BACKGROUND: The purpose of this paper is to study the utility of adhesives (artificial-cyanoacrylate and biological-fibrin glue) for improving transconjunctival sutureless vitrectomy (TSV) sclerotomy closure competency. METHODS: Experimental and observer-masked study in which after performing TSV in cadaveric pig eyes, different adhesives were tested on sclerotomy entrances in order to determine if they improved closure competency in face of progressive intraocular pressure increase. In 76 eyes cyanoacrylate-treated sclerotomies were compared with sclerotomies in which no additional manoeuvre to aid closing was performed; in 76 eyes fibrin glue with no manoeuvre; and in the last 76 eyes, cyanoacrylate-treated sclerotomies were compared with fibrin glue-treated sclerotomies. RESULTS: A total of 228 eyes had a 23-gauge TSV performed. Both cyanoacrylate and fibrin glue treated sclerotomies achieved higher mean opening pressures when compared with nontreated sclerotomies in the same eye (p < 0.002). When cyanoacrylate was compared with biological adhesive in the same eye, no statistically significant differences were obtained (p = 0.216). DISCUSSIONS: This experimental study provides support for the possible role of adhesives in improving TSV sclerotomy closure competency in clinical practice. Nature Publishing Group UK 2019-11-04 2020-07 /pmc/articles/PMC7314807/ /pubmed/31685969 http://dx.doi.org/10.1038/s41433-019-0651-4 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
López-Guajardo, Lorenzo
Benítez-Herreros, Javier
Donate-López, Juan
Opazo-Toro, Valeria
Evaluation of leakage resistance improvement in transconjunctival sutureless vitrectomy sclerotomies closed with adhesives. an experimental study
title Evaluation of leakage resistance improvement in transconjunctival sutureless vitrectomy sclerotomies closed with adhesives. an experimental study
title_full Evaluation of leakage resistance improvement in transconjunctival sutureless vitrectomy sclerotomies closed with adhesives. an experimental study
title_fullStr Evaluation of leakage resistance improvement in transconjunctival sutureless vitrectomy sclerotomies closed with adhesives. an experimental study
title_full_unstemmed Evaluation of leakage resistance improvement in transconjunctival sutureless vitrectomy sclerotomies closed with adhesives. an experimental study
title_short Evaluation of leakage resistance improvement in transconjunctival sutureless vitrectomy sclerotomies closed with adhesives. an experimental study
title_sort evaluation of leakage resistance improvement in transconjunctival sutureless vitrectomy sclerotomies closed with adhesives. an experimental study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314807/
https://www.ncbi.nlm.nih.gov/pubmed/31685969
http://dx.doi.org/10.1038/s41433-019-0651-4
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