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Role of PKC in the Regulation of the Human Kidney Chloride Channel ClC-Ka

The physiological role of the renal ClC-Ka/ClC-K1 channels is to confer a high Cl(-) permeability to the thin Ascending Limb of Henle (tAL), which in turn is essential for establishing the high osmolarity of the renal medulla that drives water reabsorption from collecting ducts. Here, we investigate...

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Detalles Bibliográficos
Autores principales: Gerbino, Andrea, De Zio, Roberta, Russo, Daniela, Milella, Luigi, Milano, Serena, Procino, Giuseppe, Pusch, Michael, Svelto, Maria, Carmosino, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314819/
https://www.ncbi.nlm.nih.gov/pubmed/32581267
http://dx.doi.org/10.1038/s41598-020-67219-8

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