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Role of PKC in the Regulation of the Human Kidney Chloride Channel ClC-Ka
The physiological role of the renal ClC-Ka/ClC-K1 channels is to confer a high Cl(-) permeability to the thin Ascending Limb of Henle (tAL), which in turn is essential for establishing the high osmolarity of the renal medulla that drives water reabsorption from collecting ducts. Here, we investigate...
Autores principales: | Gerbino, Andrea, De Zio, Roberta, Russo, Daniela, Milella, Luigi, Milano, Serena, Procino, Giuseppe, Pusch, Michael, Svelto, Maria, Carmosino, Monica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314819/ https://www.ncbi.nlm.nih.gov/pubmed/32581267 http://dx.doi.org/10.1038/s41598-020-67219-8 |
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