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Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.

BACKGROUND: Major depressive disorder and anxiety disorders are associated with less productivity, earlier retirement, and more sick-days at the workplace. These associations also exist for patients with metabolic syndrome. For both, exercise is a generally recommended part of multimodal treatments....

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Autores principales: Haufe, Sven, Kahl, Kai G., Kerling, Arno, Protte, Gudrun, Bayerle, Pauline, Stenner, Hedwig T., Rolff, Simone, Sundermeier, Thorben, Eigendorf, Julian, Kück, Momme, Hanke, Alexander A., Keller-Varady, Katriona, Ensslen, Ralf, Nachbar, Lars, Lauenstein, Dirk, Böthig, Dietmar, Terkamp, Christoph, Stiesch, Meike, Hilfiker-Kleiner, Denise, Haverich, Axel, Tegtbur, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314973/
https://www.ncbi.nlm.nih.gov/pubmed/32625123
http://dx.doi.org/10.3389/fpsyt.2020.00562
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author Haufe, Sven
Kahl, Kai G.
Kerling, Arno
Protte, Gudrun
Bayerle, Pauline
Stenner, Hedwig T.
Rolff, Simone
Sundermeier, Thorben
Eigendorf, Julian
Kück, Momme
Hanke, Alexander A.
Keller-Varady, Katriona
Ensslen, Ralf
Nachbar, Lars
Lauenstein, Dirk
Böthig, Dietmar
Terkamp, Christoph
Stiesch, Meike
Hilfiker-Kleiner, Denise
Haverich, Axel
Tegtbur, Uwe
author_facet Haufe, Sven
Kahl, Kai G.
Kerling, Arno
Protte, Gudrun
Bayerle, Pauline
Stenner, Hedwig T.
Rolff, Simone
Sundermeier, Thorben
Eigendorf, Julian
Kück, Momme
Hanke, Alexander A.
Keller-Varady, Katriona
Ensslen, Ralf
Nachbar, Lars
Lauenstein, Dirk
Böthig, Dietmar
Terkamp, Christoph
Stiesch, Meike
Hilfiker-Kleiner, Denise
Haverich, Axel
Tegtbur, Uwe
author_sort Haufe, Sven
collection PubMed
description BACKGROUND: Major depressive disorder and anxiety disorders are associated with less productivity, earlier retirement, and more sick-days at the workplace. These associations also exist for patients with metabolic syndrome. For both, exercise is a generally recommended part of multimodal treatments. However, for individuals with metabolic syndrome, in which depression and anxiety is more prevalent and severe, evidence for the efficacy of exercise interventions is limited. METHODS: Company employees with diagnosed metabolic syndrome (n=314, age: 48 ± 8 yrs) were randomized to a 6-month exercise intervention (150 min per week) or wait-list control. Participants received individual recommendations for exercise activities by personal meetings, telephone, or via a smartphone app. Physical activities were supervised and adapted using activity monitor data transferred to a central database. Work ability (work ability index), depression severity and anxiety severity [hospital anxiety and depression scale (HADS)], and health-related quality of live [short form 36 (SF-36)] were assessed. RESULTS: We included 314 subjects from which 287 finished the intervention. Total work ability, depression- and anxiety severity, and the mental component score of the SF-36 improved after 6 months exercise compared to controls. After baseline stratification for normal (HADS scores 0–7) and increased depression- and anxiety scores (HADS scores 8–21) individuals with increased severity scores had similar age, body composition, blood lipids, and cardiorespiratory fitness compared to those with normal scores, but lower total work ability and component sum scores of health-related quality of life. After 6 months total work ability increased in the exercise group compared to controls with the magnitude of the observed increase being significantly greater for subjects with increased depression- and anxiety severity at baseline compared to those with normal severity scores. CONCLUSIONS: A 6-month exercise intervention for company employees with metabolic syndrome showed strongest effects on self-perceived work ability in individuals with mild to severe depression- and anxiety severity. This suggests exercise programs offered to workers with metabolic syndrome not only reduces individual disease risk but may also reduce healthcare and employers costs arising from metabolic syndrome and mental disease conditions. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, identifier NCT03293264.
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spelling pubmed-73149732020-07-02 Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life. Haufe, Sven Kahl, Kai G. Kerling, Arno Protte, Gudrun Bayerle, Pauline Stenner, Hedwig T. Rolff, Simone Sundermeier, Thorben Eigendorf, Julian Kück, Momme Hanke, Alexander A. Keller-Varady, Katriona Ensslen, Ralf Nachbar, Lars Lauenstein, Dirk Böthig, Dietmar Terkamp, Christoph Stiesch, Meike Hilfiker-Kleiner, Denise Haverich, Axel Tegtbur, Uwe Front Psychiatry Psychiatry BACKGROUND: Major depressive disorder and anxiety disorders are associated with less productivity, earlier retirement, and more sick-days at the workplace. These associations also exist for patients with metabolic syndrome. For both, exercise is a generally recommended part of multimodal treatments. However, for individuals with metabolic syndrome, in which depression and anxiety is more prevalent and severe, evidence for the efficacy of exercise interventions is limited. METHODS: Company employees with diagnosed metabolic syndrome (n=314, age: 48 ± 8 yrs) were randomized to a 6-month exercise intervention (150 min per week) or wait-list control. Participants received individual recommendations for exercise activities by personal meetings, telephone, or via a smartphone app. Physical activities were supervised and adapted using activity monitor data transferred to a central database. Work ability (work ability index), depression severity and anxiety severity [hospital anxiety and depression scale (HADS)], and health-related quality of live [short form 36 (SF-36)] were assessed. RESULTS: We included 314 subjects from which 287 finished the intervention. Total work ability, depression- and anxiety severity, and the mental component score of the SF-36 improved after 6 months exercise compared to controls. After baseline stratification for normal (HADS scores 0–7) and increased depression- and anxiety scores (HADS scores 8–21) individuals with increased severity scores had similar age, body composition, blood lipids, and cardiorespiratory fitness compared to those with normal scores, but lower total work ability and component sum scores of health-related quality of life. After 6 months total work ability increased in the exercise group compared to controls with the magnitude of the observed increase being significantly greater for subjects with increased depression- and anxiety severity at baseline compared to those with normal severity scores. CONCLUSIONS: A 6-month exercise intervention for company employees with metabolic syndrome showed strongest effects on self-perceived work ability in individuals with mild to severe depression- and anxiety severity. This suggests exercise programs offered to workers with metabolic syndrome not only reduces individual disease risk but may also reduce healthcare and employers costs arising from metabolic syndrome and mental disease conditions. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, identifier NCT03293264. Frontiers Media S.A. 2020-06-18 /pmc/articles/PMC7314973/ /pubmed/32625123 http://dx.doi.org/10.3389/fpsyt.2020.00562 Text en Copyright © 2020 Haufe, Kahl, Kerling, Protte, Bayerle, Stenner, Rolff, Sundermeier, Eigendorf, Kück, Hanke, Keller-Varady, Ensslen, Nachbar, Lauenstein, Böthig, Terkamp, Stiesch, Hilfiker-Kleiner, Haverich and Tegtbur http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Haufe, Sven
Kahl, Kai G.
Kerling, Arno
Protte, Gudrun
Bayerle, Pauline
Stenner, Hedwig T.
Rolff, Simone
Sundermeier, Thorben
Eigendorf, Julian
Kück, Momme
Hanke, Alexander A.
Keller-Varady, Katriona
Ensslen, Ralf
Nachbar, Lars
Lauenstein, Dirk
Böthig, Dietmar
Terkamp, Christoph
Stiesch, Meike
Hilfiker-Kleiner, Denise
Haverich, Axel
Tegtbur, Uwe
Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.
title Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.
title_full Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.
title_fullStr Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.
title_full_unstemmed Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.
title_short Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.
title_sort employers with metabolic syndrome and increased depression/anxiety severity profit most from structured exercise intervention for work ability and quality of life.
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314973/
https://www.ncbi.nlm.nih.gov/pubmed/32625123
http://dx.doi.org/10.3389/fpsyt.2020.00562
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