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Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington’s Disease
Huntington’s disease (HD) is an inherited neurodegenerative disorder in which the striatum is the most affected brain region. Although a chronic inflammatory microglial reaction that amplifies disease progression has been described in HD patients, some murine models develop symptoms without inflamma...
Autores principales: | Kim, Anya, García-García, Esther, Straccia, Marco, Comella-Bolla, Andrea, Miguez, Andrés, Masana, Mercè, Alberch, Jordi, Canals, Josep M., Rodríguez, Manuel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314984/ https://www.ncbi.nlm.nih.gov/pubmed/32625064 http://dx.doi.org/10.3389/fncel.2020.00163 |
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