The Histone Demethylase JMJD1C Regulates CAMKK2-AMPK Signaling to Participate in Cardiac Hypertrophy

The roles of the histone demethylase JMJD1C in cardiac hypertrophy remain unknown. JMJD1C was overexpressed in hypertrophic hearts of humans and mice, whereas the histone methylation was reduced. Jmjd1c knockdown repressed the angiotensin II (Ang II)-mediated increase in cardiomyocyte size and overe...

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Detalles Bibliográficos
Autores principales: Yu, Shuang, Li, Yihong, Zhao, Hongwei, Wang, Qingdong, Chen, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314990/
https://www.ncbi.nlm.nih.gov/pubmed/32625104
http://dx.doi.org/10.3389/fphys.2020.00539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314990/
https://www.ncbi.nlm.nih.gov/pubmed/32625104
http://dx.doi.org/10.3389/fphys.2020.00539

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