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Development of BacMam Induced Hepatitis E Virus Replication Model in Hepatoma Cells to Study the Polyprotein Processing

The processing of polyprotein(s) to form structural and non-structural components remains an enigma due to the non-existence of an efficient and robust Hepatitis E Virus (HEV) culture system. We used the BacMam approach to construct an HEV replication model in which the HEV genome was cloned in the...

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Detalles Bibliográficos
Autores principales: Kumar, Manjeet, Hooda, Preeti, Khanna, Madhu, Patel, Utkarsh, Sehgal, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315041/
https://www.ncbi.nlm.nih.gov/pubmed/32625196
http://dx.doi.org/10.3389/fmicb.2020.01347