Primary Adrenal Insufficiency during Immune Checkpoint Inhibitor Treatment: Case Reports and Review of the Literature

As the indications and clinical use of immune checkpoint inhibitors increase, it is expected that we will face some of their less frequently reported complications. Primary adrenal insufficiency is one of them, and given its unspecific symptoms and potentially serious consequences, it is important t...

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Autores principales: Salinas, Carlos, Renner, Alex, Rojas, Carlos, Samtani, Suraj, Burotto, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315192/
https://www.ncbi.nlm.nih.gov/pubmed/32595473
http://dx.doi.org/10.1159/000507652
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author Salinas, Carlos
Renner, Alex
Rojas, Carlos
Samtani, Suraj
Burotto, Mauricio
author_facet Salinas, Carlos
Renner, Alex
Rojas, Carlos
Samtani, Suraj
Burotto, Mauricio
author_sort Salinas, Carlos
collection PubMed
description As the indications and clinical use of immune checkpoint inhibitors increase, it is expected that we will face some of their less frequently reported complications. Primary adrenal insufficiency is one of them, and given its unspecific symptoms and potentially serious consequences, it is important to have a high degree of clinical suspicion. We present 3 cases and a review of the literature concerning its main clinical characteristics, diagnostics, and management.
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spelling pubmed-73151922020-06-26 Primary Adrenal Insufficiency during Immune Checkpoint Inhibitor Treatment: Case Reports and Review of the Literature Salinas, Carlos Renner, Alex Rojas, Carlos Samtani, Suraj Burotto, Mauricio Case Rep Oncol Case Report As the indications and clinical use of immune checkpoint inhibitors increase, it is expected that we will face some of their less frequently reported complications. Primary adrenal insufficiency is one of them, and given its unspecific symptoms and potentially serious consequences, it is important to have a high degree of clinical suspicion. We present 3 cases and a review of the literature concerning its main clinical characteristics, diagnostics, and management. S. Karger AG 2020-06-09 /pmc/articles/PMC7315192/ /pubmed/32595473 http://dx.doi.org/10.1159/000507652 Text en Copyright © 2020 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Salinas, Carlos
Renner, Alex
Rojas, Carlos
Samtani, Suraj
Burotto, Mauricio
Primary Adrenal Insufficiency during Immune Checkpoint Inhibitor Treatment: Case Reports and Review of the Literature
title Primary Adrenal Insufficiency during Immune Checkpoint Inhibitor Treatment: Case Reports and Review of the Literature
title_full Primary Adrenal Insufficiency during Immune Checkpoint Inhibitor Treatment: Case Reports and Review of the Literature
title_fullStr Primary Adrenal Insufficiency during Immune Checkpoint Inhibitor Treatment: Case Reports and Review of the Literature
title_full_unstemmed Primary Adrenal Insufficiency during Immune Checkpoint Inhibitor Treatment: Case Reports and Review of the Literature
title_short Primary Adrenal Insufficiency during Immune Checkpoint Inhibitor Treatment: Case Reports and Review of the Literature
title_sort primary adrenal insufficiency during immune checkpoint inhibitor treatment: case reports and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315192/
https://www.ncbi.nlm.nih.gov/pubmed/32595473
http://dx.doi.org/10.1159/000507652
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