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Effects of a postnatal Atrx conditional knockout in neurons on autism-like behaviours in male and female mice
BACKGROUND: Alpha-thalassemia/mental retardation, X-linked, or ATRX, is an autism susceptibility gene that encodes a chromatin remodeler. Mutations of ATRX result in the ATR-X intellectual disability syndrome and have been identified in autism spectrum disorder (ASD) patients. The mechanisms by whic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315487/ https://www.ncbi.nlm.nih.gov/pubmed/32580781 http://dx.doi.org/10.1186/s11689-020-09319-0 |