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Effects of a postnatal Atrx conditional knockout in neurons on autism-like behaviours in male and female mice

BACKGROUND: Alpha-thalassemia/mental retardation, X-linked, or ATRX, is an autism susceptibility gene that encodes a chromatin remodeler. Mutations of ATRX result in the ATR-X intellectual disability syndrome and have been identified in autism spectrum disorder (ASD) patients. The mechanisms by whic...

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Detalles Bibliográficos
Autores principales: Martin-Kenny, Nicole, Bérubé, Nathalie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315487/
https://www.ncbi.nlm.nih.gov/pubmed/32580781
http://dx.doi.org/10.1186/s11689-020-09319-0