Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer

BACKGROUND: Wnt signaling drives epithelial self-renewal and disease progression in human colonic epithelium and colorectal cancer (CRC). Characterization of Wnt effector pathways is key for our understanding of these processes and for developing therapeutic strategies that aim to preserve tissue ho...

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Detalles Bibliográficos
Autores principales: Dietinger, Vanessa, García de Durango, Cira R., Wiechmann, Svenja, Boos, Sophie L., Michl, Marlies, Neumann, Jens, Hermeking, Heiko, Kuster, Bernhard, Jung, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315491/
https://www.ncbi.nlm.nih.gov/pubmed/32586342
http://dx.doi.org/10.1186/s12964-020-00561-6

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