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A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma

BACKGROUND: Patient-derived xenograft (PDX) mouse models of cancer have been recognized as better mouse models that recapitulate the characteristics of original malignancies including preserved tumor heterogeneity, lineage hierarchy, and tumor microenvironment. However, common challenges of PDX mode...

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Detalles Bibliográficos
Autores principales:	Liu, Zhenyang, Ahn, Michael Ho-Young, Kurokawa, Tomohiro, Ly, Amy, Zhang, Gong, Wang, Fuyou, Yamada, Teppei, Sadagopan, Ananthan, Cheng, Jane, Ferrone, Cristina R., Liss, Andrew S., Honselmann, Kim C., Wojtkiewicz, Gregory R., Ferrone, Soldano, Wang, Xinhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315507/ https://www.ncbi.nlm.nih.gov/pubmed/32580742 http://dx.doi.org/10.1186/s12967-020-02414-9

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