Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

BACKGROUND: Traditionally, the transcriptomic and proteomic characterisation of CD4(+) T cells at the single-cell level has been performed by two largely exclusive types of technologies: single-cell RNA sequencing (scRNA-seq) and antibody-based cytometry. Here, we present a multi-omics approach allo...

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Detalles Bibliográficos
Autores principales: Trzupek, Dominik, Dunstan, Melanie, Cutler, Antony J., Lee, Mercede, Godfrey, Leila, Jarvis, Lorna, Rainbow, Daniel B., Aschenbrenner, Dominik, Jones, Joanne L., Uhlig, Holm H., Wicker, Linda S., Todd, John A., Ferreira, Ricardo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315544/
https://www.ncbi.nlm.nih.gov/pubmed/32580776
http://dx.doi.org/10.1186/s13073-020-00756-z

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