Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS

Hospitals worldwide are experiencing a shortage in essential intravenous sedative medications. This is attributable to high number and high sedative needs of COVID-19 critical care patients with disruption of drug supply chains. Inhaled volatile anesthetic agents are an abundant resource and readily...

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Detalles Bibliográficos
Autores principales: Jerath, Angela, Ferguson, Niall D., Cuthbertson, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Narrative Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315695/
https://www.ncbi.nlm.nih.gov/pubmed/32588067
http://dx.doi.org/10.1007/s00134-020-06154-8
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author Jerath, Angela
Ferguson, Niall D.
Cuthbertson, Brian
author_facet Jerath, Angela
Ferguson, Niall D.
Cuthbertson, Brian
author_sort Jerath, Angela
collection PubMed
description Hospitals worldwide are experiencing a shortage in essential intravenous sedative medications. This is attributable to high number and high sedative needs of COVID-19 critical care patients with disruption of drug supply chains. Inhaled volatile anesthetic agents are an abundant resource and readily implementable solution for providing ICU sedation. Inhaled volatile agents may also provide important pulmonary benefits for COVID-19 patients with ARDS that could improve gas exchange and reduce time spent on a ventilator. We review the use of volatile agents, and provide a technical overview and algorithm for administering inhaled volatile-based sedation in ICUs.
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spelling pubmed-73156952020-06-25 Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS Jerath, Angela Ferguson, Niall D. Cuthbertson, Brian Intensive Care Med Narrative Review Hospitals worldwide are experiencing a shortage in essential intravenous sedative medications. This is attributable to high number and high sedative needs of COVID-19 critical care patients with disruption of drug supply chains. Inhaled volatile anesthetic agents are an abundant resource and readily implementable solution for providing ICU sedation. Inhaled volatile agents may also provide important pulmonary benefits for COVID-19 patients with ARDS that could improve gas exchange and reduce time spent on a ventilator. We review the use of volatile agents, and provide a technical overview and algorithm for administering inhaled volatile-based sedation in ICUs. Springer Berlin Heidelberg 2020-06-25 2020 /pmc/articles/PMC7315695/ /pubmed/32588067 http://dx.doi.org/10.1007/s00134-020-06154-8 Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Narrative Review
Jerath, Angela
Ferguson, Niall D.
Cuthbertson, Brian
Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS
title Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS
title_full Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS
title_fullStr Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS
title_full_unstemmed Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS
title_short Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS
title_sort inhalational volatile-based sedation for covid-19 pneumonia and ards
topic Narrative Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315695/
https://www.ncbi.nlm.nih.gov/pubmed/32588067
http://dx.doi.org/10.1007/s00134-020-06154-8
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