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Prevalence of SARS-CoV-2 specific neutralising antibodies in blood donors from the Lodi Red Zone in Lombardy, Italy, as at 06 April 2020

We evaluated SARS-CoV-2 RNA and neutralising antibodies in blood donors (BD) residing in the Lodi Red Zone, Italy. Of 390 BDs recruited after 20 February 2020 − when the first COVID-19 case in Lombardy was identified, 91 (23%) aged 19–70 years were antibody positive. Viral RNA was detected in an add...

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Detalles Bibliográficos
Autores principales: Percivalle, Elena, Cambiè, Giuseppe, Cassaniti, Irene, Nepita, Edoardo Vecchio, Maserati, Roberta, Ferrari, Alessandro, Di Martino, Raffaella, Isernia, Paola, Mojoli, Francesco, Bruno, Raffaele, Tirani, Marcello, Cereda, Danilo, Nicora, Carlo, Lombardo, Massimo, Baldanti, Fausto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315724/
https://www.ncbi.nlm.nih.gov/pubmed/32583766
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.24.2001031
Descripción
Sumario:We evaluated SARS-CoV-2 RNA and neutralising antibodies in blood donors (BD) residing in the Lodi Red Zone, Italy. Of 390 BDs recruited after 20 February 2020 − when the first COVID-19 case in Lombardy was identified, 91 (23%) aged 19–70 years were antibody positive. Viral RNA was detected in an additional 17 (4.3%) BDs, yielding ca 28% (108/390) with evidence of virus exposure. Five stored samples collected as early as 12 February were seropositive.