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Toward operationalizing deficient emotional self-regulation in newly referred adults with ADHD: A receiver operator characteristic curve analysis

BACKGROUND. A growing body of research suggests that deficient emotional self-regulation (DESR) is common and morbid among attention-deficit/hyperactivity disorder (ADHD) patients. The main aim of the present study was to assess whether high and low levels of DESR in adult ADHD patients can be opera...

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Autores principales: Biederman, Joseph, DiSalvo, Maura, Woodworth, K. Yvonne, Fried, Ronna, Uchida, Mai, Biederman, Itai, Spencer, Thomas J., Surman, Craig, Faraone, Stephen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315889/
https://www.ncbi.nlm.nih.gov/pubmed/32093797
http://dx.doi.org/10.1192/j.eurpsy.2019.11
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author Biederman, Joseph
DiSalvo, Maura
Woodworth, K. Yvonne
Fried, Ronna
Uchida, Mai
Biederman, Itai
Spencer, Thomas J.
Surman, Craig
Faraone, Stephen V.
author_facet Biederman, Joseph
DiSalvo, Maura
Woodworth, K. Yvonne
Fried, Ronna
Uchida, Mai
Biederman, Itai
Spencer, Thomas J.
Surman, Craig
Faraone, Stephen V.
author_sort Biederman, Joseph
collection PubMed
description BACKGROUND. A growing body of research suggests that deficient emotional self-regulation (DESR) is common and morbid among attention-deficit/hyperactivity disorder (ADHD) patients. The main aim of the present study was to assess whether high and low levels of DESR in adult ADHD patients can be operationalized and whether they are clinically useful. METHODS. A total of 441 newly referred 18- to 55-year-old adults of both sexes with Diagnostic and Statistical Manual of Mental Disorders: Fifth Edition (DSM-5) ADHD completed self-reported rating scales. We operationalized DESR using items from the Barkley Current Behavior Scale. We used receiver operator characteristic (ROC) curves to identify the optimal cut-off on the Barkley Emotional Dysregulation (ED) Scale to categorize patients as having high- versus low-level DESR and compared demographic and clinical characteristics between the groups. RESULTS. We averaged the optimal Barkley ED Scale cut-points from the ROC curve analyses across all subscales and categorized ADHD patients as having high- (N = 191) or low-level (N = 250) DESR (total Barkley ED Scale score ≥8 or <8, respectively). Those with high-level DESR had significantly more severe symptoms of ADHD, executive dysfunction, autistic traits, levels of psychopathology, and worse quality of life compared with those with low-level DESR. There were no major differences in outcomes among medicated and unmedicated patients. CONCLUSIONS. High levels of DESR are common in adults with ADHD and when present represent a burdensome source of added morbidity and disability worthy of further clinical and scientific attention.
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spelling pubmed-73158892020-07-07 Toward operationalizing deficient emotional self-regulation in newly referred adults with ADHD: A receiver operator characteristic curve analysis Biederman, Joseph DiSalvo, Maura Woodworth, K. Yvonne Fried, Ronna Uchida, Mai Biederman, Itai Spencer, Thomas J. Surman, Craig Faraone, Stephen V. Eur Psychiatry Research Article BACKGROUND. A growing body of research suggests that deficient emotional self-regulation (DESR) is common and morbid among attention-deficit/hyperactivity disorder (ADHD) patients. The main aim of the present study was to assess whether high and low levels of DESR in adult ADHD patients can be operationalized and whether they are clinically useful. METHODS. A total of 441 newly referred 18- to 55-year-old adults of both sexes with Diagnostic and Statistical Manual of Mental Disorders: Fifth Edition (DSM-5) ADHD completed self-reported rating scales. We operationalized DESR using items from the Barkley Current Behavior Scale. We used receiver operator characteristic (ROC) curves to identify the optimal cut-off on the Barkley Emotional Dysregulation (ED) Scale to categorize patients as having high- versus low-level DESR and compared demographic and clinical characteristics between the groups. RESULTS. We averaged the optimal Barkley ED Scale cut-points from the ROC curve analyses across all subscales and categorized ADHD patients as having high- (N = 191) or low-level (N = 250) DESR (total Barkley ED Scale score ≥8 or <8, respectively). Those with high-level DESR had significantly more severe symptoms of ADHD, executive dysfunction, autistic traits, levels of psychopathology, and worse quality of life compared with those with low-level DESR. There were no major differences in outcomes among medicated and unmedicated patients. CONCLUSIONS. High levels of DESR are common in adults with ADHD and when present represent a burdensome source of added morbidity and disability worthy of further clinical and scientific attention. Cambridge University Press 2020-02-24 /pmc/articles/PMC7315889/ /pubmed/32093797 http://dx.doi.org/10.1192/j.eurpsy.2019.11 Text en © The Author(s) 2020 http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike licence (http://creativecommons.org/licenses/by-nc-sa/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the same Creative Commons licence is included and the original work is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use.
spellingShingle Research Article
Biederman, Joseph
DiSalvo, Maura
Woodworth, K. Yvonne
Fried, Ronna
Uchida, Mai
Biederman, Itai
Spencer, Thomas J.
Surman, Craig
Faraone, Stephen V.
Toward operationalizing deficient emotional self-regulation in newly referred adults with ADHD: A receiver operator characteristic curve analysis
title Toward operationalizing deficient emotional self-regulation in newly referred adults with ADHD: A receiver operator characteristic curve analysis
title_full Toward operationalizing deficient emotional self-regulation in newly referred adults with ADHD: A receiver operator characteristic curve analysis
title_fullStr Toward operationalizing deficient emotional self-regulation in newly referred adults with ADHD: A receiver operator characteristic curve analysis
title_full_unstemmed Toward operationalizing deficient emotional self-regulation in newly referred adults with ADHD: A receiver operator characteristic curve analysis
title_short Toward operationalizing deficient emotional self-regulation in newly referred adults with ADHD: A receiver operator characteristic curve analysis
title_sort toward operationalizing deficient emotional self-regulation in newly referred adults with adhd: a receiver operator characteristic curve analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315889/
https://www.ncbi.nlm.nih.gov/pubmed/32093797
http://dx.doi.org/10.1192/j.eurpsy.2019.11
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