Negative Symptoms of Schizophrenia and Dopaminergic Transmission: Translational Models and Perspectives Opened by iPSC Techniques

Negative symptoms (NS) represent a heterogeneous dimension of schizophrenia (SCZ), associated with a poor functional outcome. A dysregulated dopamine (DA) system, including a reduced D1 receptor activation in the prefrontal cortex, DA hypoactivity in the caudate and alterations in D3 receptor activi...

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Detalles Bibliográficos
Autores principales: Collo, Ginetta, Mucci, Armida, Giordano, Giulia M., Merlo Pich, Emilio, Galderisi, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315891/
https://www.ncbi.nlm.nih.gov/pubmed/32625059
http://dx.doi.org/10.3389/fnins.2020.00632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315891/
https://www.ncbi.nlm.nih.gov/pubmed/32625059
http://dx.doi.org/10.3389/fnins.2020.00632

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