Interleukin-6 and severity of COVID-19 patients in Hefei, China

• Twenty-four out of 75 patients developed into severe condition in the course of the infection. • The prominent laboratory abnormalities of COVID patients were lymphopenia, elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH). • Elevated interleukin 6 (IL-6) correlated with decrease of...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Z., Xie, J., Yin, M., Yang, Y., Ding, C., Gao, Y., Ma, X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316053/
https://www.ncbi.nlm.nih.gov/pubmed/32593746
http://dx.doi.org/10.1016/j.medmal.2020.06.005
_version_ 1783550372410818560
author Zhao, Z.
Xie, J.
Yin, M.
Yang, Y.
Ding, C.
Gao, Y.
Ma, X.
author_facet Zhao, Z.
Xie, J.
Yin, M.
Yang, Y.
Ding, C.
Gao, Y.
Ma, X.
author_sort Zhao, Z.
collection PubMed
description • Twenty-four out of 75 patients developed into severe condition in the course of the infection. • The prominent laboratory abnormalities of COVID patients were lymphopenia, elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH). • Elevated interleukin 6 (IL-6) correlated with decrease of LYM%, CD4(+) and CD8(+) T cell counts, and increase of CRP, LDH and Procalcitonin (PCT) levels.
format Online
Article
Text
id pubmed-7316053
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier Masson SAS.
record_format MEDLINE/PubMed
spelling pubmed-73160532020-06-25 Interleukin-6 and severity of COVID-19 patients in Hefei, China Zhao, Z. Xie, J. Yin, M. Yang, Y. Ding, C. Gao, Y. Ma, X. Med Mal Infect Letter to the Editor • Twenty-four out of 75 patients developed into severe condition in the course of the infection. • The prominent laboratory abnormalities of COVID patients were lymphopenia, elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH). • Elevated interleukin 6 (IL-6) correlated with decrease of LYM%, CD4(+) and CD8(+) T cell counts, and increase of CRP, LDH and Procalcitonin (PCT) levels. Elsevier Masson SAS. 2020-10 2020-06-25 /pmc/articles/PMC7316053/ /pubmed/32593746 http://dx.doi.org/10.1016/j.medmal.2020.06.005 Text en © 2020 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Letter to the Editor
Zhao, Z.
Xie, J.
Yin, M.
Yang, Y.
Ding, C.
Gao, Y.
Ma, X.
Interleukin-6 and severity of COVID-19 patients in Hefei, China
title Interleukin-6 and severity of COVID-19 patients in Hefei, China
title_full Interleukin-6 and severity of COVID-19 patients in Hefei, China
title_fullStr Interleukin-6 and severity of COVID-19 patients in Hefei, China
title_full_unstemmed Interleukin-6 and severity of COVID-19 patients in Hefei, China
title_short Interleukin-6 and severity of COVID-19 patients in Hefei, China
title_sort interleukin-6 and severity of covid-19 patients in hefei, china
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316053/
https://www.ncbi.nlm.nih.gov/pubmed/32593746
http://dx.doi.org/10.1016/j.medmal.2020.06.005
work_keys_str_mv AT zhaoz interleukin6andseverityofcovid19patientsinhefeichina
AT xiej interleukin6andseverityofcovid19patientsinhefeichina
AT yinm interleukin6andseverityofcovid19patientsinhefeichina
AT yangy interleukin6andseverityofcovid19patientsinhefeichina
AT dingc interleukin6andseverityofcovid19patientsinhefeichina
AT gaoy interleukin6andseverityofcovid19patientsinhefeichina
AT max interleukin6andseverityofcovid19patientsinhefeichina

Ejemplares similares