Cargando…
Sarm1 knockout protects against early but not late axonal degeneration in experimental allergic encephalomyelitis
Programmed axonal degeneration, also known as Wallerian degeneration, occurs in immune-mediated central nervous system (CNS) inflammatory disorders such as multiple sclerosis and the animal model experimental allergic encephalomyelitis (EAE). Sterile alpha and TIR domain containing protein 1 (SARM1)...
Autores principales: | Viar, Kenneth, Njoku, Daniel, Secor McVoy, Julie, Oh, Unsong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316289/ https://www.ncbi.nlm.nih.gov/pubmed/32584865 http://dx.doi.org/10.1371/journal.pone.0235110 |
Ejemplares similares
-
Liver X receptor-dependent inhibition of microglial nitric oxide synthase 2
por: Secor McVoy, Julie R, et al.
Publicado: (2015) -
Multifaceted roles of SARM1 in axon degeneration and signaling
por: Waller, Thomas J., et al.
Publicado: (2022) -
TIR-1/SARM1 inhibits axon regeneration and promotes axon degeneration
por: Czech, Victoria L, et al.
Publicado: (2023) -
Astrocytic SARM1 promotes neuroinflammation and axonal demyelination in experimental autoimmune encephalomyelitis through inhibiting GDNF signaling
por: Jin, Lingting, et al.
Publicado: (2022) -
Novel role of SARM1 mediated axonal degeneration in the pathogenesis of rabies
por: Sundaramoorthy, Vinod, et al.
Publicado: (2020)