Early immune response against Fonsecaea pedrosoi requires Dectin-2-mediated Th17 activity, whereas Th1 response, aided by Treg cells, is crucial for fungal clearance in later stage of experimental chromoblastomycosis

Chromoblastomycosis (CBM) is a chronic worldwide subcutaneous mycosis, caused by several dimorphic, pigmented dematiaceous fungi. It is difficult to treat patients with the disease, mainly because of its recalcitrant nature. The correct activation of host immune response is critical to avoid fungal...

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Detalles Bibliográficos
Autores principales: Siqueira, Isaque Medeiros, Wüthrich, Marcel, Li, Mengyi, Wang, Huafeng, Las-Casas, Lucas de Oliveira, de Castro, Raffael Júnio Araújo, Klein, Bruce, Bocca, Anamelia Lorenzetti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316354/
https://www.ncbi.nlm.nih.gov/pubmed/32542003
http://dx.doi.org/10.1371/journal.pntd.0008386

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