Insulin and Proinsulin Dynamics Progressively Deteriorate From Within the Normal Range Toward Impaired Glucose Tolerance

CONTEXT: Slight elevations in plasma glucose (PG) manifest in advance of diabetes onset, but abnormalities in immunoreactive insulin (IRI), proinsulin (Pro), and adiponectin dynamics during this stage remain poorly understood. OBJECTIVE: The objective of this work is to investigate whether IRI and P...

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Detalles Bibliográficos
Autores principales: Murai, Norimitsu, Saito, Naoko, Kodama, Eriko, Iida, Tatsuya, Mikura, Kentaro, Imai, Hideyuki, Kaji, Mariko, Hashizume, Mai, Kigawa, Yasuyoshi, Koizumi, Go, Tadokoro, Rie, Sugisawa, Chiho, Endo, Kei, Iizaka, Toru, Saiki, Ryo, Otsuka, Fumiko, Ishibashi, Shun, Nagasaka, Shoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Clinical Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316365/
https://www.ncbi.nlm.nih.gov/pubmed/32617449
http://dx.doi.org/10.1210/jendso/bvaa066

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