Cargando…

Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff

Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, C., Montesinos, I., Dauby, N., Gilles, C., Dahma, H., Van Den Wijngaert, S., De Wit, S., Delforge, M., Clumeck, N., Vandenberg, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Healthcare Infection Society. Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316468/
https://www.ncbi.nlm.nih.gov/pubmed/32593608
http://dx.doi.org/10.1016/j.jhin.2020.06.028
_version_ 1783550440049213440
author Martin, C.
Montesinos, I.
Dauby, N.
Gilles, C.
Dahma, H.
Van Den Wijngaert, S.
De Wit, S.
Delforge, M.
Clumeck, N.
Vandenberg, O.
author_facet Martin, C.
Montesinos, I.
Dauby, N.
Gilles, C.
Dahma, H.
Van Den Wijngaert, S.
De Wit, S.
Delforge, M.
Clumeck, N.
Vandenberg, O.
author_sort Martin, C.
collection PubMed
description Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2 infection were confirmed by reverse transcriptase polymerase chain reaction and/or serology in 326 participants (overall infection rate 12.6%). The presence of comorbidities or symptoms at the time of sample collection was a risk factor for infection, but working as a physician/nurse was not a risk factor. Universal screening in high-risk units, irrespective of symptoms, allowed the identification of asymptomatic and potentially contagious infected workers, enabling them to self-isolate for 7 days.
format Online
Article
Text
id pubmed-7316468
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The Healthcare Infection Society. Published by Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-73164682020-06-26 Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff Martin, C. Montesinos, I. Dauby, N. Gilles, C. Dahma, H. Van Den Wijngaert, S. De Wit, S. Delforge, M. Clumeck, N. Vandenberg, O. J Hosp Infect Article Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2 infection were confirmed by reverse transcriptase polymerase chain reaction and/or serology in 326 participants (overall infection rate 12.6%). The presence of comorbidities or symptoms at the time of sample collection was a risk factor for infection, but working as a physician/nurse was not a risk factor. Universal screening in high-risk units, irrespective of symptoms, allowed the identification of asymptomatic and potentially contagious infected workers, enabling them to self-isolate for 7 days. The Healthcare Infection Society. Published by Elsevier Ltd. 2020-09 2020-06-25 /pmc/articles/PMC7316468/ /pubmed/32593608 http://dx.doi.org/10.1016/j.jhin.2020.06.028 Text en © 2020 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Martin, C.
Montesinos, I.
Dauby, N.
Gilles, C.
Dahma, H.
Van Den Wijngaert, S.
De Wit, S.
Delforge, M.
Clumeck, N.
Vandenberg, O.
Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff
title Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff
title_full Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff
title_fullStr Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff
title_full_unstemmed Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff
title_short Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff
title_sort dynamics of sars-cov-2 rt-pcr positivity and seroprevalence among high-risk healthcare workers and hospital staff
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316468/
https://www.ncbi.nlm.nih.gov/pubmed/32593608
http://dx.doi.org/10.1016/j.jhin.2020.06.028
work_keys_str_mv AT martinc dynamicsofsarscov2rtpcrpositivityandseroprevalenceamonghighriskhealthcareworkersandhospitalstaff
AT montesinosi dynamicsofsarscov2rtpcrpositivityandseroprevalenceamonghighriskhealthcareworkersandhospitalstaff
AT daubyn dynamicsofsarscov2rtpcrpositivityandseroprevalenceamonghighriskhealthcareworkersandhospitalstaff
AT gillesc dynamicsofsarscov2rtpcrpositivityandseroprevalenceamonghighriskhealthcareworkersandhospitalstaff
AT dahmah dynamicsofsarscov2rtpcrpositivityandseroprevalenceamonghighriskhealthcareworkersandhospitalstaff
AT vandenwijngaerts dynamicsofsarscov2rtpcrpositivityandseroprevalenceamonghighriskhealthcareworkersandhospitalstaff
AT dewits dynamicsofsarscov2rtpcrpositivityandseroprevalenceamonghighriskhealthcareworkersandhospitalstaff
AT delforgem dynamicsofsarscov2rtpcrpositivityandseroprevalenceamonghighriskhealthcareworkersandhospitalstaff
AT clumeckn dynamicsofsarscov2rtpcrpositivityandseroprevalenceamonghighriskhealthcareworkersandhospitalstaff
AT vandenbergo dynamicsofsarscov2rtpcrpositivityandseroprevalenceamonghighriskhealthcareworkersandhospitalstaff