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Kisspeptin and neurokinin B interactions in modulating gonadotropin secretion in women with polycystic ovary syndrome

STUDY QUESTION: What is the role of the hypothalamic neuropeptide neurokinin B (NKB) and its interaction with kisspeptin on GnRH/LH secretion in women with polycystic ovary syndrome (PCOS)? SUMMARY ANSWER: Administration of neurokinin 3 receptor antagonist (NK3Ra) for 7 days reduced LH and FSH secre...

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Detalles Bibliográficos
Autores principales: Skorupskaite, Karolina, George, Jyothis T, Veldhuis, Johannes D, Millar, Robert P, Anderson, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316500/
https://www.ncbi.nlm.nih.gov/pubmed/32510130
http://dx.doi.org/10.1093/humrep/deaa104