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Association between Knee Osteoarthritis and Metabolic Syndrome in Non-Institutionalized Elderly Patients

Objective  This study aimed to analyze the association between knee osteoarthritis (OA) and metabolic syndrome (MS) in non-institutionalized elderly patients. Methods  A cross-sectional, randomized study, drawn from a probabilistic cluster study conducted with 416 elderly people from a Family Health...

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Autores principales: Franco, Maura Fernandes, Falsarella, Glaucia Regina, Costallat, Beatriz Lavras, Coimbra, Ibsen Bellini, Coimbra, Arlete Maria Valente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Ortopedia e Traumatologia. Published by Thieme Revinter Publicações Ltda 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316545/
https://www.ncbi.nlm.nih.gov/pubmed/32616976
http://dx.doi.org/10.1055/s-0040-1701281
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author Franco, Maura Fernandes
Falsarella, Glaucia Regina
Costallat, Beatriz Lavras
Coimbra, Ibsen Bellini
Coimbra, Arlete Maria Valente
author_facet Franco, Maura Fernandes
Falsarella, Glaucia Regina
Costallat, Beatriz Lavras
Coimbra, Ibsen Bellini
Coimbra, Arlete Maria Valente
author_sort Franco, Maura Fernandes
collection PubMed
description Objective  This study aimed to analyze the association between knee osteoarthritis (OA) and metabolic syndrome (MS) in non-institutionalized elderly patients. Methods  A cross-sectional, randomized study, drawn from a probabilistic cluster study conducted with 416 elderly people from a Family Health Unit (USF, in the Portuguese acronym) of our municipality. Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III), and OA according to the Kellgren-Lawrence (KL) scale (≥ 2). Results  For the statistical analysis, we performed an exploratory data analysis, Mann-Whitney or Chi-Squared tests and univariate and multivariate logistic regressions, with significance level of p  < 0.05; the concordance between the evaluators was verified through the Kappa coefficient. There was an association between OA and body mass index (BMI) ( p  = 0.0021) and between OA and waist circumference (WC) ( p  < 0.001; odds ratio [OR] = 3.524). There was no significant association between OA and the number of metabolic components nor with SM itself. Conclusion  We conclude that knee OA is associated with WC, regardless of weight, and that the increase in its measure reflects a greater chance of MS in non-institutionalized elderly patients.
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spelling pubmed-73165452020-07-01 Association between Knee Osteoarthritis and Metabolic Syndrome in Non-Institutionalized Elderly Patients Franco, Maura Fernandes Falsarella, Glaucia Regina Costallat, Beatriz Lavras Coimbra, Ibsen Bellini Coimbra, Arlete Maria Valente Rev Bras Ortop (Sao Paulo) Objective  This study aimed to analyze the association between knee osteoarthritis (OA) and metabolic syndrome (MS) in non-institutionalized elderly patients. Methods  A cross-sectional, randomized study, drawn from a probabilistic cluster study conducted with 416 elderly people from a Family Health Unit (USF, in the Portuguese acronym) of our municipality. Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III), and OA according to the Kellgren-Lawrence (KL) scale (≥ 2). Results  For the statistical analysis, we performed an exploratory data analysis, Mann-Whitney or Chi-Squared tests and univariate and multivariate logistic regressions, with significance level of p  < 0.05; the concordance between the evaluators was verified through the Kappa coefficient. There was an association between OA and body mass index (BMI) ( p  = 0.0021) and between OA and waist circumference (WC) ( p  < 0.001; odds ratio [OR] = 3.524). There was no significant association between OA and the number of metabolic components nor with SM itself. Conclusion  We conclude that knee OA is associated with WC, regardless of weight, and that the increase in its measure reflects a greater chance of MS in non-institutionalized elderly patients. Sociedade Brasileira de Ortopedia e Traumatologia. Published by Thieme Revinter Publicações Ltda 2020-06 2020-03-16 /pmc/articles/PMC7316545/ /pubmed/32616976 http://dx.doi.org/10.1055/s-0040-1701281 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Franco, Maura Fernandes
Falsarella, Glaucia Regina
Costallat, Beatriz Lavras
Coimbra, Ibsen Bellini
Coimbra, Arlete Maria Valente
Association between Knee Osteoarthritis and Metabolic Syndrome in Non-Institutionalized Elderly Patients
title Association between Knee Osteoarthritis and Metabolic Syndrome in Non-Institutionalized Elderly Patients
title_full Association between Knee Osteoarthritis and Metabolic Syndrome in Non-Institutionalized Elderly Patients
title_fullStr Association between Knee Osteoarthritis and Metabolic Syndrome in Non-Institutionalized Elderly Patients
title_full_unstemmed Association between Knee Osteoarthritis and Metabolic Syndrome in Non-Institutionalized Elderly Patients
title_short Association between Knee Osteoarthritis and Metabolic Syndrome in Non-Institutionalized Elderly Patients
title_sort association between knee osteoarthritis and metabolic syndrome in non-institutionalized elderly patients
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316545/
https://www.ncbi.nlm.nih.gov/pubmed/32616976
http://dx.doi.org/10.1055/s-0040-1701281
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