Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria

Plasmodium parasite-specific antibodies are critical for protection against malaria, yet the development of long-lived and effective humoral immunity against Plasmodium takes many years and multiple rounds of infection and cure. Here we report that the rapid development of short-lived plasmablasts d...

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Detalles Bibliográficos
Autores principales: Vijay, Rahul, Guthmiller, Jenna J., Sturtz, Alexandria J., Surette, Fionna A., Rogers, Kai J., Sompallae, Ramakrishna R., Li, Fengyin, Pope, Rosemary L., Chan, Jo-Anne, de Labastida Rivera, Fabian, Andrew, Dean, Webb, Lachlan, Maury, Wendy J., Xue, Hai-Hui, Engwerda, Christian R., McCarthy, James S., Boyle, Michelle J., Butler, Noah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316608/
https://www.ncbi.nlm.nih.gov/pubmed/32424361
http://dx.doi.org/10.1038/s41590-020-0678-5

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