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RNA-seq reveals altered gene expression levels in proximal tubular cell cultures compared to renal cortex but not during early glucotoxicity

Cell cultures are often used to study physiological processes in health and disease. It is well-known that cells change their gene expression in vitro compared to in vivo, but it is rarely experimentally addressed. High glucose is a known trigger of apoptosis in proximal tubular cells (PTC). Here we...

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Detalles Bibliográficos
Autores principales: Nilsson, Linnéa M., Castresana-Aguirre, Miguel, Scott, Lena, Brismar, Hjalmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316724/
https://www.ncbi.nlm.nih.gov/pubmed/32587318
http://dx.doi.org/10.1038/s41598-020-67361-3