Cargando…

Growth Factor Midkine Aggravates Pulmonary Arterial Hypertension via Surface Nucleolin

Pulmonary arterial hypertension (PAH) is a progressive fatal disease caused by pulmonary arterial remodeling. Midkine regulates cell proliferation and migration, and it is induced by hypoxia, but its roles in pulmonary arterial remodeling remain unclear. Serum midkine levels were significantly incre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kinoshita, Daisuke, Shishido, Tetsuro, Takahashi, Tetsuya, Yokoyama, Miyuki, Sugai, Takayuki, Watanabe, Ken, Tamura, Harutoshi, Nishiyama, Satoshi, Takahashi, Hiroki, Arimoto, Takanori, Miyamoto, Takuya, Watanabe, Tetsu, Kishida, Satoshi, Kadomatsu, Kenji, Abe, Jun-ichi, Takeishi, Yasuchika, Konta, Tsuneo, Kubota, Isao, Watanabe, Masafumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316741/ https://www.ncbi.nlm.nih.gov/pubmed/32587339 http://dx.doi.org/10.1038/s41598-020-67217-w

Ejemplares similares

Impact of Iron Deficiency on Peripheral Artery Disease After Endovascular Therapy
por: Otaki, Yoichiro, et al.
Publicado: (2019)

Cardiac Nuclear High-Mobility Group Box 1 Ameliorates Pathological Cardiac Hypertrophy by Inhibiting DNA Damage Response
por: Takahashi, Tetsuya, et al.
Publicado: (2019)

The impact of physical activity on cardiovascular mortality in the general population
por: Takahashi, Tetsuya, et al.
Publicado: (2021)

Impact of Impaired Pancreatic β-Cell Function on Cardiovascular Prognosis in Heart Failure Patients Without Diabetes Mellitus
por: Narumi, Taro, et al.
Publicado: (2019)

Endovascular Revascularization Improves the Central Hemodynamics and Augmentation Index in Patients with Peripheral Artery Disease
por: Watanabe, Ken, et al.
Publicado: (2019)

Deficiency of Senescence Marker Protein 30 Exacerbates Cardiac Injury after Ischemia/Reperfusion
por: Kadowaki, Shinpei, et al.
Publicado: (2016)

Impact of plasma xanthine oxidoreductase activity in patients with heart failure with preserved ejection fraction
por: Watanabe, Ken, et al.
Publicado: (2020)

Effects of Nitric Oxide Synthase 3 Gene Polymorphisms on Cardiovascular Events in a General Japanese Population　― The Yamagata (Takahata) Study ―
por: Saito, Yuji, et al.
Publicado: (2022)

Brain Natriuretic Peptide (BNP) and N-Terminal-proBNP in Cardio-Renal Anemia Syndrome　― Difference in Prognostic Ability ―
por: Otaki, Yoichiro, et al.
Publicado: (2019)

Impact of serum omentin-1 levels on cardiac prognosis in patients with heart failure
por: Narumi, Taro, et al.
Publicado: (2014)

Left atrial strain as evaluated by two-dimensional speckle tracking predicts left atrial appendage dysfunction in patients with acute ischemic stroke
por: Sasaki, Shintaro, et al.
Publicado: (2014)

The association between microRNA-21 and hypertension-induced cardiac remodeling
por: Watanabe, Ken, et al.
Publicado: (2020)

Impact of Insulin Resistance on Silent and Ongoing Myocardial Damage in Normal Subjects: The Takahata Study
por: Narumi, Taro, et al.
Publicado: (2012)

The Impact of Superoxide Dismutase-1 Genetic Variation on Cardiovascular and All-Cause Mortality in a Prospective Cohort Study: The Yamagata (Takahata) Study
por: Otaki, Yoichiro, et al.
Publicado: (2016)

Association of the Aspartate Aminotransferase to Alanine Aminotransferase Ratio with BNP Level and Cardiovascular Mortality in the General Population: The Yamagata Study 10-Year Follow-Up
por: Yokoyama, Miyuki, et al.
Publicado: (2016)

The obesity paradox is not observed in chronic heart failure patients with metabolic syndrome
por: Narumi, Taro, et al.
Publicado: (2014)

Impact of Modified H(2)FPEF Score on Chronic Limb-Threatening Ischemia in Patients With Lower Extremity Artery Disease Who Underwent Endovascular Therapy
por: Shikama, Taku, et al.
Publicado: (2022)

Gender Differences in the Impact of Plasma Xanthine Oxidoreductase Activity on Coronary Artery Spasm
por: Watanabe, Ken, et al.
Publicado: (2021)

Prognostic Impact of Renal Dysfunction at 1-Year Follow-Up on Clinical Outcomes After Percutaneous Coronary Intervention
por: Takahashi, Tetsuya, et al.
Publicado: (2023)

The association between defibrillation shock energy and acute cardiac damage in patients with implantable cardioverter defibrillators
por: Ishigaki, Daisuke, et al.
Publicado: (2016)

Heart-type fatty acid binding protein and high-sensitivity troponin T are myocardial damage markers that could predict adverse clinical outcomes in patients with peripheral artery disease
por: Otaki, Yoichiro, et al.
Publicado: (2015)

Combined assessment of myocardial damage and electrical disturbance in chronic heart failure
por: Kadowaki, Shinpei, et al.
Publicado: (2017)

Association of Heart-Type Fatty Acid-Binding Protein with Cardiovascular Risk Factors and All-Cause Mortality in the General Population: The Takahata Study
por: Otaki, Yoichiro, et al.
Publicado: (2014)

Long Pentraxin PTX3 Exacerbates Pressure Overload–Induced Left Ventricular Dysfunction
por: Suzuki, Satoshi, et al.
Publicado: (2013)

Association of malnutrition with renal dysfunction and clinical outcome in patients with heart failure
por: Otaki, Yoichiro, et al.
Publicado: (2022)

Growth Differentiation Factor-15 and Clinical Outcomes in Japanese Patients With Ischemic Heart Disease
por: Kobayashi, Yuta, et al.
Publicado: (2023)

Renal tubular damage and clinical outcome in heart failure with preserved ejection fraction and chronic kidney disease
por: Otaki, Yoichiro, et al.
Publicado: (2023)

Cardiac nuclear high mobility group box 1 prevents the development of cardiac hypertrophy and heart failure
por: Funayama, Akira, et al.
Publicado: (2013)

Midkine in repair of the injured nervous system
por: Yoshida, Yoshihiro, et al.
Publicado: (2014)

Senescence Marker Protein 30 Has a Cardio-Protective Role in Doxorubicin-Induced Cardiac Dysfunction
por: Miyata, Makiko, et al.
Publicado: (2013)

Differential regulation of diacylglycerol kinase isoform in human failing hearts
por: Bilim, Olga, et al.
Publicado: (2011)

Midkine induces the transformation of NIH3T3 cells.
por: Kadomatsu, K., et al.
Publicado: (1997)

Involvement of midkine in the development of pulmonary fibrosis
por: Misa, Kenichi, et al.
Publicado: (2017)

Increased Midkine Gene Expression in Human Gastrointestinal Cancers
por: Aridome, Kuniaki, et al.
Publicado: (1995)

Decreased cardiac mortality with nicorandil in patients with ischemic heart failure
por: Yoshihisa, Akiomi, et al.
Publicado: (2017)

Associations between acylcarnitine to free carnitine ratio and adverse prognosis in heart failure patients with reduced or preserved ejection fraction
por: Yoshihisa, Akiomi, et al.
Publicado: (2017)

HECT‐Type Ubiquitin E3 Ligase ITCH Interacts With Thioredoxin‐Interacting Protein and Ameliorates Reactive Oxygen Species–Induced Cardiotoxicity
por: Otaki, Yoichiro, et al.
Publicado: (2016)

A promoter region of the midkine gene that is frequently expressed in human hepatocellular carcinoma can activate a suicide gene as effectively as the α-fetoprotein promoter
por: Tomizawa, M, et al.
Publicado: (2003)

Expression of midkine in the early stage of carcinogenesis in human colorectal cancer
por: Ye, C, et al.
Publicado: (1999)

Correlation of elevated level of blood midkine with poor prognostic factors of human neuroblastomas
por: Ikematsu, S, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_b5cton8n7me71locajbts46ucd