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Estimation of homeostatic dysregulation and frailty using biomarker variability: a principal component analysis of hemodialysis patients

Increased intraindividual variability in several biological parameters is associated with aspects of frailty and may reflect impaired physiological regulation. As frailty involves a cumulative decline in multiple physiological systems, we aimed to estimate the overall regulatory capacity by applying...

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Detalles Bibliográficos
Autores principales:	Nakazato, Yuichi, Sugiyama, Tomoko, Ohno, Rena, Shimoyama, Hirofumi, Leung, Diana L., Cohen, Alan A., Kurane, Riichi, Hirose, Satoru, Watanabe, Akihisa, Shimoyama, Hiromi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316742/ https://www.ncbi.nlm.nih.gov/pubmed/32587279 http://dx.doi.org/10.1038/s41598-020-66861-6

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