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Hybrid PET/MRI enables high-spatial resolution, quantitative imaging of amyloid plaques in an Alzheimer’s disease mouse model
The emergence of PET probes for amyloid plaques and neurofibrillary tangles, hallmarks of Alzheimer disease (AD), enables monitoring of pathology in AD mouse models. However, small-animal PET imaging is limited by coarse spatial resolution. We have installed a custom-fabricated PET insert into our s...
Autores principales: | Frost, Georgia R., Longo, Valerie, Li, Thomas, Jonas, Lauren A., Judenhofer, Martin, Cherry, Simon, Koutcher, Jason, Lekaye, Carl, Zanzonico, Pat, Li, Yue-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316864/ https://www.ncbi.nlm.nih.gov/pubmed/32587315 http://dx.doi.org/10.1038/s41598-020-67284-z |
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