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Hybrid PET/MRI enables high-spatial resolution, quantitative imaging of amyloid plaques in an Alzheimer’s disease mouse model

The emergence of PET probes for amyloid plaques and neurofibrillary tangles, hallmarks of Alzheimer disease (AD), enables monitoring of pathology in AD mouse models. However, small-animal PET imaging is limited by coarse spatial resolution. We have installed a custom-fabricated PET insert into our s...

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Detalles Bibliográficos
Autores principales: Frost, Georgia R., Longo, Valerie, Li, Thomas, Jonas, Lauren A., Judenhofer, Martin, Cherry, Simon, Koutcher, Jason, Lekaye, Carl, Zanzonico, Pat, Li, Yue-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316864/
https://www.ncbi.nlm.nih.gov/pubmed/32587315
http://dx.doi.org/10.1038/s41598-020-67284-z

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