Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in mdx Mice

Duchenne muscular dystrophy (DMD) is characterized by rapid wasting of skeletal muscle. Mitochondrial dysfunction is a well-known pathological feature of DMD. However, whether mitochondrial dysfunction occurs before muscle fiber damage in DMD pathology is not well known. Furthermore, the impact upon...

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Detalles Bibliográficos
Autores principales: Moore, Timothy M., Lin, Amanda J., Strumwasser, Alexander R., Cory, Kevin, Whitney, Kate, Ho, Theodore, Ho, Timothy, Lee, Joseph L., Rucker, Daniel H., Nguyen, Christina Q., Yackly, Aidan, Mahata, Sushil K., Wanagat, Jonathan, Stiles, Linsey, Turcotte, Lorraine P., Crosbie, Rachelle H., Zhou, Zhenqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317021/
https://www.ncbi.nlm.nih.gov/pubmed/32636760
http://dx.doi.org/10.3389/fphys.2020.00690

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