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Pharmacological Manipulation of K(v)7 Channels as a New Therapeutic Tool for Multiple Brain Disorders
K(v)7 (“M-type,” KCNQ) K(+) currents, play dominant roles in controlling neuronal excitability. They act as a “brake” against hyperexcitable states in the central and peripheral nervous systems. Pharmacological augmentation of M current has been developed for controlling epileptic seizures, although...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317068/ https://www.ncbi.nlm.nih.gov/pubmed/32636759 http://dx.doi.org/10.3389/fphys.2020.00688 |