Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss

BACKGROUND: Alopecia areata (AA) is considered a highly heritable, T-cell-mediated autoimmune disease of the hair follicle. However, no convincing susceptibility gene has yet been pinpointed in the major histocompatibility complex (MHC), a genome region known to be associated with AA as compared to...

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Detalles Bibliográficos
Autores principales: Oka, Akira, Takagi, Atsushi, Komiyama, Etsuko, Yoshihara, Nagisa, Mano, Shuhei, Hosomichi, Kazuyoshi, Suzuki, Shingo, Haida, Yuko, Motosugi, Nami, Hatanaka, Tomomi, Kimura, Minoru, Ueda, Mahoko Takahashi, Nakagawa, So, Miura, Hiromi, Ohtsuka, Masato, Tanaka, Masayuki, Komiyama, Tomoyoshi, Otomo, Asako, Hadano, Shinji, Mabuchi, Tomotaka, Beck, Stephan, Inoko, Hidetoshi, Ikeda, Shigaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317227/
https://www.ncbi.nlm.nih.gov/pubmed/32580135
http://dx.doi.org/10.1016/j.ebiom.2020.102810

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