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DISC1 Regulates Mitochondrial Trafficking in a Miro1-GTP-Dependent Manner

The disrupted in schizophrenia 1 (DISC1) protein is implicated in major mental illnesses including schizophrenia and bipolar disorder. A key feature of psychiatric disease is aberrant synaptic communication. Correct synaptic transmission is dependent on spatiotemporally regulated energy provision an...

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Detalles Bibliográficos
Autores principales: Norkett, Rosalind, Lesept, Flavie, Kittler, Josef T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317294/
https://www.ncbi.nlm.nih.gov/pubmed/32637409
http://dx.doi.org/10.3389/fcell.2020.00449